Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation

SARS-CoV-2 has developed a number of Variants of Concern (VOC) with increased infectivity and/or reduced recognition by neutralizing antibodies specific for the receptor binding domain (RBD) of the spike protein. Extended studies of other viruses have shown that strong and broad viral escape from ne...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 14; p. 1114396
Main Authors:	Chang, Xinyue, Liu, Xuelan, Martina, Byron, Zeltins, Andris, Augusto, Gilles, Vogel, Monique, Mohsen, Mona O., Speiser, Daniel E., Bachmann, Martin F.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 10.02.2023
Subjects:	Animals Antibodies, Neutralizing antibody COVID-19 - prevention & control immune escape Immunization Immunology Mice SARS-CoV-2 - genetics SARS–CoV–2 serotype Vaccination variants SARS–CoV–2 immune escape antibody variants serotype
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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