Effect of Physical and Chemical Hair Removal Methods on Skin Barrier Function in vitro: Consequences for a Hydrophilic Model Permeant

Background: Although very common in our society, the effect of hair removal on physiological skin parameters and on the ingress of applied chemicals has not been systematically investigated. Thus, as a first step, the aim of the present study was to elucidate the effect of hair removal through epila...

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Published in:Skin pharmacology and physiology Vol. 32; no. 1; pp. 8 - 21
Main Authors: Pany, Astrid, Klang, Victoria, Brunner, Marion, Ruthofer, Johanna, Schwarz, Elisabeth, Valenta, Claudia
Format: Journal Article
Language:English
Published: Basel, Switzerland S. Karger AG 01.01.2019
Subjects:
Care and treatment
Depilatories
Hair
Health aspects
Infrared spectroscopy
Methods
Physiological aspects
Raman spectroscopy
Removal
Research Article
Skin
Skin care products
Austria
Germany
Shaving
Skin barrier function
Damaged skin
Hair removal
Skin/material interaction
ISSN:1660-5527, 1660-5535, 1660-5535
Online Access:Get full text
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Summary:Background: Although very common in our society, the effect of hair removal on physiological skin parameters and on the ingress of applied chemicals has not been systematically investigated. Thus, as a first step, the aim of the present study was to elucidate the effect of hair removal through epilation (electric epilation, waxing) and depilation (dry and wet shaving, depilatory cream) on skin properties in vitro using the porcine ear model. Methods: Attenuated total reflection Fourier transform infrared spectroscopy, measurement of the transepidermal water loss (TEWL), visualization by capacitance-based contact imaging, confocal Raman spectroscopy (CRS), diffusion cell studies and tape stripping experiments were employed. Results: Increased TEWL and altered skin permittivity maps were observed. Decreased stratum corneum thickness was observed after waxing. Diffusion cell studies showed increased skin permeation especially in case of dry shaving, electric epilation and waxing. Conclusion: Considering CRS and diffusion cell data, a moderate if significant decrease in skin barrier function was found after hair removal by dry shaving (physical skin/material interaction) and epilation methods (plucking out the entire hair, for example, by electrical epilation and waxing). Subsequent experiments will include testing of different permeants covering a broad range of physicochemical properties in vitro and confirming our findings in vivo.
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ISSN:1660-5527
1660-5535
1660-5535
DOI:10.1159/000493168