Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo

Atherosclerosis, the build-up of occlusive, lipid-rich plaques in arterial walls, is a focal trigger of chronic coronary, intracranial, and peripheral arterial diseases, which together account for the leading causes of death worldwide. Although the directed treatment of atherosclerotic plaques remai...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS Jg. 112; H. 9; S. 2693
Hauptverfasser:	Lewis, Daniel R, Petersen, Latrisha K, York, Adam W, Zablocki, Kyle R, Joseph, Laurie B, Kholodovych, Vladyslav, Prud'homme, Robert K, Uhrich, Kathryn E, Moghe, Prabhas V
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 03.03.2015
Schlagworte:	Animals Atherosclerosis - drug therapy Atherosclerosis - genetics Atherosclerosis - metabolism Atherosclerosis - pathology Carbohydrates CD36 Antigens - genetics CD36 Antigens - metabolism Humans Hyperplasia - genetics Hyperplasia - metabolism Hyperplasia - pathology Lipids Macrophages - metabolism Macrophages - pathology Mice Mice, Knockout Nanoparticles Neointima - genetics Neointima - metabolism Neointima - pathology Oxidation-Reduction Plaque, Atherosclerotic - blood Plaque, Atherosclerotic - drug therapy Plaque, Atherosclerotic - genetics Plaque, Atherosclerotic - metabolism Plaque, Atherosclerotic - pathology Scavenger Receptors, Class A - genetics Scavenger Receptors, Class A - metabolism atherosclerosis nanomedicine macrophages biomaterials
ISSN:	1091-6490, 1091-6490
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!