Modeling treatment effect modification in multidrug-resistant tuberculosis in an individual patientdata meta-analysis

Effect modification occurs while the effect of the treatment is not homogeneous across the different strata of patient characteristics. When the effect of treatment may vary from individual to individual, precision medicine can be improved by identifying patient covariates to estimate the size and d...

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Vydané v:	Statistical methods in medical research Ročník 31; číslo 4; s. 689
Hlavní autori:	Liu, Yan, Schnitzer, Mireille E, Wang, Guanbo, Kennedy, Edward, Viiklepp, Piret, Vargas, Mario H, Sotgiu, Giovanni, Menzies, Dick, Benedetti, Andrea
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.04.2022
Predmet:	Biometry Humans Observational Studies as Topic Tuberculosis, Multidrug-Resistant - drug therapy Conditional average treatment effect individual patient data targeted maximum likelihood estimation meta-analysis multidrug-resistant tuberculosis double robustness marginal structural model
ISSN:	1477-0334, 1477-0334
On-line prístup:	Zistit podrobnosti o prístupe
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