Expression of Immune Related Genes and Possible Regulatory Mechanisms in Alzheimer’s Disease

Immune infiltration of peripheral natural killer (NK) cells in the brain has been observed in Alzheimer’s disease (AD). Immunity-related genes (IRGs) play an essential role in immune infiltration; however, the expression of IRGs and possible regulatory mechanisms involved in AD remain unclear. The p...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 12; p. 768966
Main Authors:	Lu, Yanjun, Li, Ke, Hu, Yu, Wang, Xiong
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 05.11.2021
Subjects:	Alzheimer Disease - blood Alzheimer Disease - genetics Alzheimer’s disease Brain - metabolism Brain - pathology Cells, Cultured Cluster Analysis Databases, Genetic Gene Ontology Gene Regulatory Networks Humans immune infiltration Immunity - genetics immunity related genes Immunology Killer Cells, Natural - cytology Killer Cells, Natural - metabolism Leukocytes, Mononuclear - metabolism NK cells RNA-Seq - methods Single-Cell Analysis - methods single-cell sequencing Transcription Factors - genetics Transcriptome - genetics single-cell sequencing NK cells immunity related genes Alzheimer’s disease immune infiltration
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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