Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by beta-coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has rapidly spread across the globe starting from February 2020. It is well established that during viral infection, extracellular vesicles become...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 12; p. 785941
Main Authors:	Pesce, Elisa, Manfrini, Nicola, Cordiglieri, Chiara, Santi, Spartaco, Bandera, Alessandra, Gobbini, Andrea, Gruarin, Paola, Favalli, Andrea, Bombaci, Mauro, Cuomo, Alessandro, Collino, Federica, Cricrì, Giulia, Ungaro, Riccardo, Lombardi, Andrea, Mangioni, Davide, Muscatello, Antonio, Aliberti, Stefano, Blasi, Francesco, Gori, Andrea, Abrignani, Sergio, De Francesco, Raffaele, Biffo, Stefano, Grifantini, Renata
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 17.01.2022
Subjects:	Acute Disease Adaptive Immunity Adult Aged antigen-presenting cells (APCs) COVID-19 COVID-19 - blood COVID-19 - immunology exosomes Exosomes - immunology Exosomes - metabolism Female Humans immune activation Immunology Male Middle Aged Plasma SARS-CoV-2 SARS-CoV-2 - immunology SARS-CoV-2 - metabolism soluble mediators in immunity Spike Glycoprotein, Coronavirus - blood Spike Glycoprotein, Coronavirus - immunology COVID-19 SARS-CoV-2 soluble mediators in immunity antigen-presenting cells (APCs) exosomes immune activation
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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