No bidirectional relationship between depression and periodontitis: A genetic correlation and Mendelian randomization study

Observational and research suggested a bidirectional relationship between depression and periodontitis. We estimated the genetic correlation and examined directionality of causation. The study used summary statistics from published genome wide association studies, with sample sizes ranging from 45,5...

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Veröffentlicht in:	Frontiers in immunology Jg. 13; S. 918404
Hauptverfasser:	Nolde, Michael, Holtfreter, Birte, Kocher, Thomas, Alayash, Zoheir, Reckelkamm, Stefan Lars, Ehmke, Benjamin, Baurecht, Hansjörg, Baumeister, Sebastian-Edgar
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 22.07.2022
Schlagworte:	depression Depression - genetics genetic correlation genetic correlation analysis Genome-Wide Association Study Humans Immunology Linkage Disequilibrium mendelian randomization analysis Mendelian Randomization Analysis - methods periodontitis Periodontitis - genetics genetic correlation analysis depression genetic correlation mendelian randomization analysis periodontitis
ISSN:	1664-3224, 1664-3224
Online-Zugang:	Volltext
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