Plasmacytoid Dendritic Cells Depletion and Elevation of IFN-γ Dependent Chemokines CXCL9 and CXCL10 in Children With Multisystem Inflammatory Syndrome

SARS-CoV-2 occurs in the majority of children as COVID-19, without symptoms or with a paucisymptomatic respiratory syndrome, but a small proportion of children develop the systemic Multi Inflammatory Syndrome (MIS-C), characterized by persistent fever and systemic hyperinflammation, with some clinic...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 12; p. 654587
Main Authors:	Caldarale, Francesca, Giacomelli, Mauro, Garrafa, Emirena, Tamassia, Nicola, Morreale, Alessia, Poli, Piercarlo, Timpano, Silviana, Baresi, Giulia, Zunica, Fiammetta, Cattalini, Marco, Moratto, Daniele, Chiarini, Marco, Cannizzo, Elvira Stefania, Marchetti, Giulia, Cassatella, Marco Antonio, Taddio, Andrea, Tommasini, Alberto, Badolato, Raffaele
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 26.03.2021
Subjects:	Chemokine CXCL10 - immunology Chemokine CXCL9 - immunology Child Child, Preschool COVID-19 COVID-19 - immunology CXCL10 CXCL9 Dendritic Cells - immunology Female Humans IFN Immunology Infant Interferon-gamma - immunology Male multisystem inflammatory syndrome in children Plasma Cells - immunology plasmacytoid DCs Retrospective Studies SARS-CoV-2 - immunology Systemic Inflammatory Response Syndrome - immunology COVID-19 IFN neutrophil activation CXCL10 CXCL9 plasmacytoid DCs multisystem inflammatory syndrome in children
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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