An Image Analysis Pipeline for Quantifying the Features of Fluorescently-Labeled Biomolecular Condensates in Cells

Biomolecular condensates are cellular organelles formed through liquid-liquid phase separation (LLPS) that play critical roles in cellular functions including signaling, transcription, translation, and stress response. Importantly, condensate misregulation is associated with human diseases, includin...

Full description

Bibliographic Details

Published in:	Frontiers in bioinformatics Vol. 2; p. 897238
Main Authors:	Baggett, David W., Medyukhina, Anna, Tripathi, Swarnendu, Shirnekhi, Hazheen K., Wu, Huiyun, Pounds, Stanley B., Khairy, Khaled, Kriwacki, Richard
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 06.06.2022
Subjects:	Bioinformatics biomolecular condensate fluorescence microscopy image analysis liquid-liquid phase separation open-source software puncta features biomolecular condensate open-source software liquid-liquid phase separation fluorescence microscopy image analysis puncta features
ISSN:	2673-7647, 2673-7647
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!