Heightened Circulating Interferon-Inducible Chemokines, and Activated Pro-Cytolytic Th1-Cell Phenotype Features Covid-19 Aggravation in the Second Week of Illness

Covid-19 features a delayed onset of critical illness occurring approximately one week from the beginning of symptoms, which corresponds to the bridging of innate and adaptive immunity. We reasoned that the immune events occurring at the turning point of disease might mark the direction toward patho...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 11; p. 580987
Main Authors:	Tincati, Camilla, Cannizzo, E. Stefania, Giacomelli, Mauro, Badolato, Raffaele, d’Arminio Monforte, Antonella, Marchetti, Giulia
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 20.10.2020
Subjects:	Aged Chemokines - blood Covid-19 COVID-19 - blood COVID-19 - immunology COVID-19 - virology Female Humans immunity Immunology immunopathology Interferons - blood Leukocytes, Mononuclear - immunology Male Middle Aged Phenotype S/M/N protein-reactive T-cells SARS-CoV-2 SARS-CoV-2 - genetics SARS-CoV-2 - physiology Th1 Cells - immunology SARS-CoV-2 immunopathology immunity Covid-19 S/M/N protein-reactive T-cells
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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