Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel

To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs) cause atherosclerotic cardiovascular disease (ASCVD). We assessed whether the association between LDL and ASCVD fulfils the criteria for causality by evaluating the totality of evidence from genetic studies, prospecti...

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Veröffentlicht in:	European heart journal Jg. 38; H. 32; S. 2459
Hauptverfasser:	Ference, Brian A, Ginsberg, Henry N, Graham, Ian, Ray, Kausik K, Packard, Chris J, Bruckert, Eric, Hegele, Robert A, Krauss, Ronald M, Raal, Frederick J, Schunkert, Heribert, Watts, Gerald F, Borén, Jan, Fazio, Sergio, Horton, Jay D, Masana, Luis, Nicholls, Stephen J, Nordestgaard, Børge G, van de Sluis, Bart, Taskinen, Marja-Riitta, Tokgözoglu, Lale, Landmesser, Ulf, Laufs, Ulrich, Wiklund, Olov, Stock, Jane K, Chapman, M John, Catapano, Alberico L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 21.08.2017
Schlagworte:	Anticholesteremic Agents - therapeutic use Atherosclerosis - etiology Atherosclerosis - prevention & control Cholesterol, HDL - metabolism Cholesterol, LDL - metabolism Consensus Epidemiologic Methods Ezetimibe - therapeutic use Genetic Predisposition to Disease - genetics Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hyperlipidemias - prevention & control Lipoproteins, LDL - physiology PCSK9 Inhibitors Low-density lipoprotein Recommendations Atherosclerosis Ezetimibe Clinical trials Cardiovascular disease PCSK9 Mendelian randomization Statin Causality
ISSN:	1522-9645, 1522-9645
Online-Zugang:	Weitere Angaben
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