Getting out what you put in: Copper in mitochondria and its impacts on human disease

Mitochondria accumulate copper in their matrix for the eventual maturation of the cuproenzymes cytochrome c oxidase and superoxide dismutase. Transport into the matrix is achieved by mitochondrial carrier family (MCF) proteins. The major copper transporting MCF described to date in yeast is Pic2, wh...

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Bibliographic Details
Published in:	Biochimica et biophysica acta. Molecular cell research Vol. 1868; no. 1; p. 118867
Main Authors:	Cobine, Paul A., Moore, Stanley A., Leary, Scot C.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.01.2021
Subjects:	Copper Copper - metabolism Cytochrome c oxidase Electron Transport Complex IV - genetics Electron Transport Complex IV - metabolism Humans Mitochondria Mitochondria - genetics Mitochondria - metabolism Mitochondrial carrier family Mitochondrial Proteins - genetics Molecular Chaperones - genetics Phosphate Transport Proteins - genetics Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Superoxide dismutase Superoxide Dismutase - genetics Superoxide Dismutase - metabolism Cytochrome c oxidase Superoxide dismutase Mitochondria Mitochondrial carrier family Copper
ISSN:	0167-4889, 1879-2596, 1879-2596
Online Access:	Get full text
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