Genomic Characterisation of the Indigenous Irish Kerry Cattle Breed

Kerry cattle are an endangered landrace heritage breed of cultural importance to Ireland. In the present study we have used genome-wide SNP array data to evaluate genomic diversity within the Kerry population and between Kerry cattle and other European breeds. Patterns of genetic differentiation and...

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Published in:Frontiers in genetics Vol. 9; p. 51
Main Authors: Browett, Sam, McHugo, Gillian, Richardson, Ian W., Magee, David A., Park, Stephen D. E., Fahey, Alan G., Kearney, John F., Correia, Carolina N., Randhawa, Imtiaz A. S., MacHugh, David E.
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 19.02.2018
Subjects:
cattle
conservation genomics
endangered breed
genetic diversity
Genetics
inbreeding
population genomics
genetic diversity
conservation genomics
single nucleotide polymorphism
population genomics
selection signature
cattle
inbreeding
endangered breed
ISSN:1664-8021, 1664-8021
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Summary:Kerry cattle are an endangered landrace heritage breed of cultural importance to Ireland. In the present study we have used genome-wide SNP array data to evaluate genomic diversity within the Kerry population and between Kerry cattle and other European breeds. Patterns of genetic differentiation and gene flow among breeds using phylogenetic trees with ancestry graphs highlighted historical gene flow from the British Shorthorn breed into the ancestral population of modern Kerry cattle. Principal component analysis (PCA) and genetic clustering emphasised the genetic distinctiveness of Kerry cattle relative to comparator British and European cattle breeds. Modelling of genetic effective population size ( ) revealed a demographic trend of diminishing over time and that recent estimated values for the Kerry breed may be less than the threshold for sustainable genetic conservation. In addition, analysis of genome-wide autozygosity ( ) showed that genomic inbreeding has increased significantly during the 20 years between 1992 and 2012. Finally, signatures of selection revealed genomic regions subject to natural and artificial selection as Kerry cattle adapted to the climate, physical geography and agro-ecology of southwest Ireland.
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Reviewed by: Gábor Mészáros, University of Natural Resources and Life Sciences, Vienna, Austria; Paolo Ajmone Marsan, Università Cattolica del Sacro Cuore, Italy
Edited by: Ino Curik, Faculty of Agriculture, University of Zagreb, Croatia
This article was submitted to Livestock Genomics, a section of the journal Frontiers in Genetics
ISSN:1664-8021
1664-8021
DOI:10.3389/fgene.2018.00051