Intracameral antibiotics: Safety, efficacy, and preparation

Endophthalmitis is a rare but potentially devastating complication of cataract surgery. This article presents an overview of endophthalmitis prophylaxis and the use of intracameral antibiotics. It highlights available intracameral antibiotics with respect to pharmacology, spectrum of activity, dosag...

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Bibliographic Details
Published in:Journal of cataract and refractive surgery Vol. 40; no. 12; p. 2134
Main Authors: Braga-Mele, Rosa, Chang, David F, Henderson, Bonnie An, Mamalis, Nick, Talley-Rostov, Audrey, Vasavada, Abhay
Format: Journal Article
Language:English
Published: United States 01.12.2014
Subjects:
Anterior Chamber - drug effects
Anti-Bacterial Agents - adverse effects
Anti-Bacterial Agents - therapeutic use
Antibiotic Prophylaxis
Cataract Extraction
Cephalosporins - adverse effects
Cephalosporins - therapeutic use
Endophthalmitis - microbiology
Endophthalmitis - prevention & control
Eye Infections, Bacterial - microbiology
Eye Infections, Bacterial - prevention & control
Fluoroquinolones - adverse effects
Fluoroquinolones - therapeutic use
Humans
Pharmaceutical Preparations
Treatment Outcome
Vancomycin - adverse effects
Vancomycin - therapeutic use
ISSN:1873-4502, 1873-4502
Online Access:Get more information
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Summary:Endophthalmitis is a rare but potentially devastating complication of cataract surgery. This article presents an overview of endophthalmitis prophylaxis and the use of intracameral antibiotics. It highlights available intracameral antibiotics with respect to pharmacology, spectrum of activity, dosage and preparation, safety, and efficacy profiles, as well as toxic anterior segment syndrome risks to better define the potential use of these medications in the prevention of endophthalmitis. Proprietary or commercial disclosures are listed after the references.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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ISSN:1873-4502
1873-4502
DOI:10.1016/j.jcrs.2014.10.010