Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

The analysis of phenotypic characteristics on (MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) and for monitoring treatment success. We therefore studied phenotypic changes on MTB-specific CD4 T cells upon anti-tuberculosis treatment initiation in relatio...

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Veröffentlicht in:	Frontiers in immunology Jg. 9; S. 2247
Hauptverfasser:	Ahmed, Mohamed I. M., Ntinginya, Nyanda E., Kibiki, Gibson, Mtafya, Bariki A, Semvua, Hadija, Mpagama, Stellah, Mtabho, Charles, Saathoff, Elmar, Held, Kathrin, Loose, Rebecca, Kroidl, Inge, Chachage, Mkunde, Both, Ulrich von, Haule, Antelmo, Mekota, Anna-Maria, Boeree, Martin J., Gillespie, Stephen H., Hoelscher, Michael, Heinrich, Norbert, Geldmacher, Christof
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 28.09.2018
Schlagworte:	biomarker Immunology Mycobacterium tuberculosis-specific T cells serial sputum culture TAM-TB assay treatment monitoring tuberculosis TAM-TB assay biomarker treatment monitoring Mycobacterium tuberculosis-specific T cells tuberculosis serial sputum culture
ISSN:	1664-3224, 1664-3224
Online-Zugang:	Volltext
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