Cell-Cycle Therapeutics Come of Age

The ability to sustain unscheduled proliferation is a hallmark of cancer. The normal process of cell division occurs via the cell cycle, a series of highly regulated steps that are orchestrated at the molecular level by specific cyclins that act in association with cyclin-dependent kinases (CDKs). C...

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Vydané v:	Journal of clinical oncology Ročník 35; číslo 25; s. 2949
Hlavní autori:	Ingham, Matthew, Schwartz, Gary K
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.09.2017
Predmet:	Animals Cell Cycle - drug effects Cell Cycle - physiology Cyclin-Dependent Kinase 4 - antagonists & inhibitors Cyclin-Dependent Kinase 6 - antagonists & inhibitors Humans Neoplasms - drug therapy Neoplasms - enzymology Neoplasms - pathology Protein Kinase Inhibitors
ISSN:	1527-7755, 1527-7755
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