Ketamine and Active Ketamine Metabolites Regulate STAT3 and the Type I Interferon Pathway in Human Microglia: Molecular Mechanisms Linked to the Antidepressant Effects of Ketamine

Inflammation is an important biological process which contributes to risk for depression, in part as a result of the production of proinflammatory cytokines and of alterations in glutamatergic neurotransmission. Ketamine has anti-inflammatory properties which might contribute to its antidepressant e...

Celý popis

Podrobná bibliografia

Vydané v:	Frontiers in pharmacology Ročník 10; s. 1302
Hlavní autori:	Ho, Ming-Fen, Zhang, Cheng, Zhang, Lingxin, Li, Hu, Weinshilboum, Richard M.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland Frontiers Media S.A 05.11.2019
Predmet:	antidepressant gene expression ketamine microglia Pharmacology RNA-seq RNA-seq ketamine microglia gene expression antidepressant
ISSN:	1663-9812, 1663-9812
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!