Colorectal cancer screening: An updated review of the available options

Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. However, colon cancer incidence and mortality is declining over the past decade owing to adoption of effective screening programs. Nevertheless, in some parts of the world, CRC incidence and mortality remain on the...

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Vydané v:World journal of gastroenterology : WJG Ročník 23; číslo 28; s. 5086
Hlavní autori: Issa, Iyad A, Noureddine, Malak
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 28.07.2017
Predmet:
Colonoscopy - economics
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - economics
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - prevention & control
Cost-Benefit Analysis
Early Detection of Cancer - economics
Early Detection of Cancer - methods
Early Detection of Cancer - standards
Guideline Adherence
Health Care Costs
Humans
Incidence
Mass Screening - economics
Mass Screening - methods
Mass Screening - standards
Occult Blood
Risk Assessment
Screening
Colonoscopy
Colorectal cancer
Fecal DNA test
Blood DNA test
Occult blood
Guidelines
ISSN:2219-2840, 2219-2840
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Popis
Shrnutí:Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. However, colon cancer incidence and mortality is declining over the past decade owing to adoption of effective screening programs. Nevertheless, in some parts of the world, CRC incidence and mortality remain on the rise, likely due to factors including "westernized" diet, lifestyle, and lack of health-care infrastructure and resources. Participation and adherence to different national screening programs remain obstacles limiting the achievement of screening goals. Different modalities are available ranging from stool based tests to radiology and endoscopy with varying sensitivity and specificity. However, the availability of these tests is limited to areas with high economic resources. Recently, FDA approved a blood-based test (Epi procolon ) for CRC screening. This blood based test may serve to increase the participation and adherence rates. Hence, leading to increase in colon cancer detection and prevention. This article will discuss various CRC screening tests with a particular focus on the data regarding the new approved blood test. Finally, we will propose an algorithm for a simple cost-effective CRC screening program.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:2219-2840
2219-2840
DOI:10.3748/wjg.v23.i28.5086