Left ventricular hypertrophy and hypertension

Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage. In addition to being a marker of HTN, LV geometrical changes: concentric remodeling, concentric or eccentric LV hypertr...

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Vydáno v:Progress in cardiovascular diseases Ročník 63; číslo 1; s. 10 - 21
Hlavní autoři: Yildiz, Mehmet, Oktay, Ahmet Afşin, Stewart, Merrill H., Milani, Richard V., Ventura, Hector O., Lavie, Carl J.
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Elsevier Inc 01.01.2020
Témata:
RCT
HTN
MRI
STE
DM
LV
BP
2D
ASE
ESC
ESH
MI
CKD
SBP
ACC
EF
ACE
AF
CAD
ECG
RWT
CR
CVD
3D
HCM
SCD
AHA
HF
LVH
ISSN:0033-0620, 1873-1740, 1532-8643, 1873-1740
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Popis
Shrnutí:Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage. In addition to being a marker of HTN, LV geometrical changes: concentric remodeling, concentric or eccentric LV hypertrophy (LVH) are major independent risk factors for not only CVD morbidity and mortality but also for all-cause mortality and neurological pathologies. Blood pressure control with lifestyle changes and antihypertensive agents has been demonstrated to prevent and regress LVH. Herein, we provide a comprehensive review of literature on the relationship between HTN and LV geometry abnormalities with a focus on diagnosis, prognosis, pathophysiological mechanisms, and treatment approaches.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:0033-0620
1873-1740
1532-8643
1873-1740
DOI:10.1016/j.pcad.2019.11.009