CSL112 enhances biomarkers of reverse cholesterol transport after single and multiple infusions in healthy subjects

The ability of apolipoprotein A-I (apoA-I) to transport cholesterol from atherosclerotic plaque is thought to underlie its inverse correlation with cardiovascular risk. To gauge the potential of infused apoA-I to transport cholesterol, we quantified cholesterol transport markers in human subjects in...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology Jg. 34; H. 9; S. 2106
Hauptverfasser:	Gille, Andreas, Easton, Rachael, D'Andrea, Denise, Wright, Samuel D, Shear, Charles L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2014
Schlagworte:	Adult Apolipoprotein A-I - metabolism ATP Binding Cassette Transporter 1 - blood Biological Transport Biomarkers Cholesterol - blood Cholesterol Esters - metabolism Cholesterol, HDL - blood Dose-Response Relationship, Drug Female Humans Infusions, Intravenous Lipoproteins, HDL - administration & dosage Lipoproteins, HDL - pharmacokinetics Lipoproteins, HDL - pharmacology Male Phosphatidylcholine-Sterol O-Acyltransferase - metabolism Young Adult reverse cholesterol transport acute coronary syndrome CSL112
ISSN:	1524-4636, 1524-4636
Online-Zugang:	Weitere Angaben
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