Novel Immunohistochemical Profiling of Small-Cell Lung Cancer: Correlations Between Tumor Subtypes and Immune Microenvironment

Background/Objectives: Small-cell lung cancer (SCLC) is a highly aggressive malignancy with an emerging molecular classification based on the expression of the transcription factors ASCL1, NEUROD1, and POU2F3. This study aimed to explore the relationship between these novel subtypes and the tumor im...

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Veröffentlicht in:	Diagnostics (Basel) Jg. 14; H. 23; S. 2660
Hauptverfasser:	Vigdorovits, Alon, Olteanu, Gheorghe-Emilian, Pascalau, Andrei-Vasile, Pirlog, Radu, Berindan-Neagoe, Ioana, Pop, Ovidiu-Laurean
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 01.12.2024
Schlagworte:	Biopsy Cancer therapies Chemotherapy Cloning Development and progression Gene expression Genetic aspects Health aspects Histology Kinases Ligands Lung cancer Lung cancer, Small cell Lymphocytes Medical prognosis Metastasis molecular classification Mortality Mutation Patients Physiological aspects Prognosis SCLC TILs Transcription factors tumor immune microenvironment Tumors Romania United States > US SCLC TILs tumor immune microenvironment molecular classification
ISSN:	2075-4418, 2075-4418
Online-Zugang:	Volltext
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