Ebola Virus Persistence in Breast Milk After No Reported Illness: A Likely Source of Virus Transmission From Mother to Child

A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly sugge...

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Vydané v:	Clinical infectious diseases Ročník 64; číslo 4; s. 513
Hlavní autori:	Sissoko, Daouda, Keïta, Mory, Diallo, Boubacar, Aliabadi, Negar, Fitter, David L, Dahl, Benjamin A, Akoi Bore, Joseph, Raymond Koundouno, Fara, Singethan, Katrin, Meisel, Sarah, Enkirch, Theresa, Mazzarelli, Antonio, Amburgey, Victoria, Faye, Ousmane, Alpha Sall, Amadou, Magassouba, N'Faly, Carroll, Miles W, Anglaret, Xavier, Malvy, Denis, Formenty, Pierre, Bruce Aylward, Raymond, Keïta, Sakoba, Harouna Djingarey, Mamoudou, Loman, Nicholas J, Günther, Stephan, Duraffour, Sophie
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.02.2017
Predmet:	Adult Cluster Analysis Ebolavirus - isolation & purification Female Hemorrhagic Fever, Ebola - transmission Humans Infant Infectious Disease Transmission, Vertical Male Milk, Human - virology Phylogeny RNA, Viral - genetics RNA, Viral - isolation & purification Semen - virology Sequence Analysis, DNA Sequence Homology Young Adult Ebola virus real-time sequencing breast milk asymptomatic carriage mother-to-child transmission
ISSN:	1537-6591, 1537-6591
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Popis
Shrnutí:	A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother's breast milk and the father's seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.
Bibliografia:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1537-6591 1537-6591
DOI:	10.1093/cid/ciw793