Frailty and Cardiovascular Health

The incidence of frailty and cardiovascular disease (CVD) increases as the population ages. There is a bidirectional relationship between frailty and CVD, and both conditions share several risk factors and underlying biological mechanisms. Frailty has been established as an independent prognostic ma...

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Veröffentlicht in:Journal of the American Heart Association Jg. 13; H. 15; S. e031736
Hauptverfasser: James, Kirstyn, Jamil, Yasser, Kumar, Manish, Kwak, Min J., Nanna, Michael G., Qazi, Saadia, Troy, Aaron L., Butt, Jawad H., Damluji, Abdulla A., Forman, Daniel E., Orkaby, Ariela R.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England John Wiley and Sons Inc 06.08.2024
Wiley
Schlagworte:
Aged
aging
cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - prevention & control
cardiovascular interventions
Contemporary Review
Frail Elderly
frailty
Frailty - complications
Frailty - diagnosis
Frailty - epidemiology
Geriatric Assessment - methods
geriatric syndromes
Heart Disease Risk Factors
Humans
Incidence
primary prevention
Prognosis
Risk Assessment
Risk Factors
frailty
geriatric syndromes
secondary prevention
cardiovascular interventions
primary prevention
aging
cardiovascular diseases
ISSN:2047-9980, 2047-9980
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Zusammenfassung:The incidence of frailty and cardiovascular disease (CVD) increases as the population ages. There is a bidirectional relationship between frailty and CVD, and both conditions share several risk factors and underlying biological mechanisms. Frailty has been established as an independent prognostic marker in patients with CVD. Moreover, its presence significantly influences both primary and secondary prevention strategies for adults with CVD while also posing a barrier to the inclusion of these patients in pivotal clinical trials and advanced cardiac interventions. This review discusses the current knowledge base on the relationship between frailty and CVD, how managing CVD risk factors can modify frailty, the influence of frailty on CVD management, and future directions for frailty detection and modification in patients with CVD.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
K. James and Y. Jamil are co‐first authors.
For Sources of Funding and Disclosures, see page 15.
This article was sent to Tiffany M. Powell‐Wiley, MD, MPH, Associate Editor, for review by expert referees, editorial decision, and final disposition.
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.123.031736