Frailty and Cardiovascular Health
The incidence of frailty and cardiovascular disease (CVD) increases as the population ages. There is a bidirectional relationship between frailty and CVD, and both conditions share several risk factors and underlying biological mechanisms. Frailty has been established as an independent prognostic ma...
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| Vydáno v: | Journal of the American Heart Association Ročník 13; číslo 15; s. e031736 |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
England
John Wiley and Sons Inc
06.08.2024
Wiley |
| Témata: | |
| ISSN: | 2047-9980, 2047-9980 |
| On-line přístup: | Získat plný text |
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| Shrnutí: | The incidence of frailty and cardiovascular disease (CVD) increases as the population ages. There is a bidirectional relationship between frailty and CVD, and both conditions share several risk factors and underlying biological mechanisms. Frailty has been established as an independent prognostic marker in patients with CVD. Moreover, its presence significantly influences both primary and secondary prevention strategies for adults with CVD while also posing a barrier to the inclusion of these patients in pivotal clinical trials and advanced cardiac interventions. This review discusses the current knowledge base on the relationship between frailty and CVD, how managing CVD risk factors can modify frailty, the influence of frailty on CVD management, and future directions for frailty detection and modification in patients with CVD. |
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| Bibliografie: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 K. James and Y. Jamil are co‐first authors. For Sources of Funding and Disclosures, see page 15. This article was sent to Tiffany M. Powell‐Wiley, MD, MPH, Associate Editor, for review by expert referees, editorial decision, and final disposition. |
| ISSN: | 2047-9980 2047-9980 |
| DOI: | 10.1161/JAHA.123.031736 |