Low-frequency conductivity tensor of rat brain tissues inferred from diffusion MRI

Conductivity tensor maps of the rat brain were obtained using diffusion magnetic resonance imaging (MRI). Signal attenuations in the cortex and the corpus callosum were measured using the stimulated echo acquisition mode (STEAM) sequence with b factors up to 6000 s/mm2. Our previously published meth...

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Veröffentlicht in:Bioelectromagnetics Jg. 30; H. 6; S. 489 - 499
Hauptverfasser: Sekino, Masaki, Ohsaki, Hiroyuki, Yamaguchi-Sekino, Sachiko, Iriguchi, Norio, Ueno, Shoogo
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.09.2009
Schlagworte:
Algorithms
Animals
Anisotropy
Brain - physiology
Brain Mapping - methods
Cerebral Cortex - physiology
conductivity
Corpus Callosum - physiology
Diffusion Magnetic Resonance Imaging - methods
Electric Conductivity
magnetic resonance
Male
Models, Neurological
Rats
Rats, Wistar
ISSN:0197-8462, 1521-186X, 1521-186X
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Zusammenfassung:Conductivity tensor maps of the rat brain were obtained using diffusion magnetic resonance imaging (MRI). Signal attenuations in the cortex and the corpus callosum were measured using the stimulated echo acquisition mode (STEAM) sequence with b factors up to 6000 s/mm2. Our previously published method was improved to infer 3 × 3 conductivity tensor at the low‐frequency limit. The conductivity tensor of the tissue was inferred from the fast component of the diffusion tensor and a fraction of the fast component. The mean conductivity (MC) of the cortex and the corpus callosum was 0.52 and 0.62 S/m, respectively. Diffusion‐weighted images were obtained with b factors up to 4500 s/mm2. Conductivity tensor images were calculated from the fast diffusion tensor images. Tissues with highly anisotropic cellular structures, such as the corpus callosum, the internal capsule, and the trigeminal nerve, exhibited high anisotropy in conductivity. The resulting values corresponded to conductivities at the low‐frequency limit because our method assumed electric currents flowing only through extracellular fluid. Bioelectromagnetics 30:489–499, 2009. © 2009 Wiley‐Liss, Inc.
Bibliographie:Gran-in-Aid for Young Scientists(A) - No. 18680037
ArticleID:BEM20505
istex:0F7DF5D43D75118BCAD948B7E5E376F40909E183
ark:/67375/WNG-PQ0324G2-5
Ministry of Education, Culture, Sports, Science and Technology, Japan
Grant-in-Aid for Scientific Research(s) - No. 17100006
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0197-8462
1521-186X
1521-186X
DOI:10.1002/bem.20505