Targeted therapy for colorectal cancer metastases: A review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of metastatic colorectal cancer

Despite recent advances in the management of colorectal cancer, metastatic disease remains challenging, and patients are rarely cured. However, a better understanding of the pathways implicated in the evolution and proliferation of cancer cells has led to the development of targeted therapies, that...

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Bibliographic Details
Published in:	Cancer Vol. 125; no. 23; pp. 4139 - 4147
Main Authors:	Piawah, Sorbarikor, Venook, Alan P.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.12.2019
Subjects:	Angiogenesis inhibitors Biomarkers Cancer Cancer therapies Cell proliferation Chemotherapy Colorectal cancer Colorectal carcinoma Cytotoxicity Disease control Epidermal growth factor Epidermal growth factor receptors Growth factors Immunotherapy Metastases Metastasis molecular targeted therapy Mutation Oncology tumor biomarkers Tumors metastases molecular targeted therapy colorectal cancer tumor biomarkers immunotherapy
ISSN:	0008-543X, 1097-0142, 1097-0142
Online Access:	Get full text
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