Factors and Pathways Modulating Endothelial Cell Senescence in Vascular Aging

Aging causes a progressive decline in the structure and function of organs. With advancing age, an accumulation of senescent endothelial cells (ECs) contributes to the risk of developing vascular dysfunction and cardiovascular diseases, including hypertension, diabetes, atherosclerosis, and neurodeg...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 23; no. 17; p. 10135
Main Authors:	Hwang, Hyun Jung, Kim, Nayeon, Herman, Allison B., Gorospe, Myriam, Lee, Jae-Seon
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 04.09.2022 MDPI
Subjects:	Age Aging Apoptosis Atherosclerosis Autophagy Cardiovascular disease Cell cycle Chemokines Coronary vessels Cyclin-dependent kinases Cytokines DNA damage Endothelium Enzymes Hypertension Kinases Metabolism Mitochondria Nitric oxide Oxidative stress Phosphorylation Physiology Polyploidy Proteins Review Veins & arteries
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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