Inhibition of SLC drug transporter activities by environmental bisphenols

The plastic component bisphenol A (BPA) is suspected to exert deleterious effects towards human health and targets various cellular and molecular pathways, including activity of ATP-binding cassette drug transporters. The present study was designed to determine whether BPA and some derivatives, like...

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Veröffentlicht in:	Toxicology in vitro Jg. 40; S. 34 - 44
Hauptverfasser:	Bruyere, Arnaud, Hubert, Céline, Le Vee, Marc, Chedik, Lisa, Sayyed, Katia, Stieger, Bruno, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.04.2017 Elsevier Science Ltd Elsevier
Schlagworte:	ABC transporters Adenosine triphosphate Benzhydryl Compounds - pharmacology Bisphenol A Bisphenol F Bisphenol S Bisphenols Cell Line, Tumor Drug transporters Ecology, environment Estrogens Flame retardants HEK293 Cells Humans Inhibition Life Sciences Oct-2 protein Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors Organic Anion Transporters, Sodium-Independent - genetics Organic Anion Transporters, Sodium-Independent - metabolism Organic Cation Transport Proteins - antagonists & inhibitors Organic Cation Transport Proteins - genetics Organic Cation Transport Proteins - metabolism Phenols Phenols - pharmacology Polybrominated Biphenyls - pharmacology Polycarbonate resins Sulfones - pharmacology Tetrabromobisphenol A Bisphenol A Bisphenol F Inhibition Tetrabromobisphenol A Bisphenol S Drug transporters
ISSN:	0887-2333, 1879-3177, 1879-3177
Online-Zugang:	Volltext
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