Laser Interstitial Thermal Therapy for Radionecrosis

Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors di...

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Bibliographic Details
Published in:Neurosurgery clinics of North America Vol. 34; no. 2; p. 209
Main Authors: Terrapon, Alexis Paul Romain, Krüger, Marie, Hundsberger, Thomas, Neidert, Marian Christoph, Bozinov, Oliver
Format: Journal Article
Language:English
Published: United States 01.04.2023
Subjects:
Brain Neoplasms - surgery
Humans
Hyperthermia, Induced
Laser Therapy
Lasers
Prospective Studies
Recurrence
Outcome
Review
Safety
Radiotherapy
Ablation
LITT
Radiation necrosis
ISSN:1558-1349, 1558-1349
Online Access:Get more information
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Summary:Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors discuss the available evidence. Most studies found a positive safety/efficacy profile, as LITT may help to lengthen survival, prevent progression, taper steroids, and improve neurological symptoms while remaining safe. Prospective studies on this subject are needed and may result in LITT becoming an essential therapeutic option for the treatment of RN.
Bibliography:ObjectType-Article-1
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ISSN:1558-1349
1558-1349
DOI:10.1016/j.nec.2022.11.001