Laser Interstitial Thermal Therapy for Radionecrosis

Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors di...

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Vydané v:Neurosurgery clinics of North America Ročník 34; číslo 2; s. 209
Hlavní autori: Terrapon, Alexis Paul Romain, Krüger, Marie, Hundsberger, Thomas, Neidert, Marian Christoph, Bozinov, Oliver
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.04.2023
Predmet:
Brain Neoplasms - surgery
Humans
Hyperthermia, Induced
Laser Therapy
Lasers
Prospective Studies
Recurrence
Outcome
Review
Safety
Radiotherapy
Ablation
LITT
Radiation necrosis
ISSN:1558-1349, 1558-1349
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Popis
Shrnutí:Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors discuss the available evidence. Most studies found a positive safety/efficacy profile, as LITT may help to lengthen survival, prevent progression, taper steroids, and improve neurological symptoms while remaining safe. Prospective studies on this subject are needed and may result in LITT becoming an essential therapeutic option for the treatment of RN.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1558-1349
1558-1349
DOI:10.1016/j.nec.2022.11.001