Laser Interstitial Thermal Therapy for Radionecrosis

Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors di...

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Vydáno v:Neurosurgery clinics of North America Ročník 34; číslo 2; s. 209
Hlavní autoři: Terrapon, Alexis Paul Romain, Krüger, Marie, Hundsberger, Thomas, Neidert, Marian Christoph, Bozinov, Oliver
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.04.2023
Témata:
Brain Neoplasms - surgery
Humans
Hyperthermia, Induced
Laser Therapy
Lasers
Prospective Studies
Recurrence
Outcome
Review
Safety
Radiotherapy
Ablation
LITT
Radiation necrosis
ISSN:1558-1349, 1558-1349
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Shrnutí:Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors discuss the available evidence. Most studies found a positive safety/efficacy profile, as LITT may help to lengthen survival, prevent progression, taper steroids, and improve neurological symptoms while remaining safe. Prospective studies on this subject are needed and may result in LITT becoming an essential therapeutic option for the treatment of RN.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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ISSN:1558-1349
1558-1349
DOI:10.1016/j.nec.2022.11.001