Design and Implementation of a Dashboard for Drug Interactions Mediated by Cytochromes Using a Health Care Data Warehouse in a University Hospital Center: Development Study

The enzymatic system of cytochrome P450 (CYP450) is a group of enzymes involved in the metabolism of drugs present in the liver. Literature records instances of underdosing of drugs due to the concurrent administration of another drug that strongly induces the same cytochrome for which the first dru...

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Bibliographic Details
Published in:	JMIR medical informatics Vol. 12; p. e57705
Main Authors:	Gosselin, Laura, Maes, Alexandre, Eyer, Kevin, Dahamna, Badisse, Disson, Flavien, Darmoni, Stefan, Wils, Julien, Grosjean, Julien
Format:	Journal Article
Language:	English
Published:	Canada JMIR Publications 28.11.2024
Subjects:	Adverse Drug Events Detection, Pharmacovigilance and Surveillance Automation Case Study Computer Science Cytochrome Cytochrome P-450 Enzyme System - metabolism Data processing Data warehouses Data Warehousing Decision Support for Health Professionals Design Drug dosages Drug Interactions Electronic Health Records Enzymes Genomics and Bioinformatics for Clinical Use Health care Hospitals, University Human subjects Humans Information Retrieval Life Sciences Medication Metabolism Metabolites Metadata Morphine Multilingualism Ontology Original Paper Pharmaceutical sciences Prescription drugs Quality Improvement Queries Questionnaires Tools, Programs and Algorithms Toxicity Visualization information system development pharmaceutical visualization drugs medication develop warehousing warehouse personalized medicine cytochrome pharmacotherapy design pharmacology interaction pharmaceutic pharmacy adverse drug-drug interaction dashboard
ISSN:	2291-9694, 2291-9694
Online Access:	Get full text
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