Cellular Origin and Functional Relevance of Collagen I Production in the Kidney

Interstitial fibrosis is associated with chronic renal failure. In addition to fibroblasts, bone marrow-derived cells and tubular epithelial cells have the capacity to produce collagen. However, the amount of collagen produced by each of these cell types and the relevance of fibrosis to renal functi...

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Bibliographic Details
Published in:	Journal of the American Society of Nephrology Vol. 29; no. 7; p. 1859
Main Authors:	Buchtler, Simone, Grill, Alexandra, Hofmarksrichter, Stefanie, Stöckert, Petra, Schiechl-Brachner, Gabriela, Rodriguez Gomez, Manuel, Neumayer, Sophia, Schmidbauer, Kathrin, Talke, Yvonne, Klinkhammer, Barbara M, Boor, Peter, Medvinsky, Alexander, Renner, Kerstin, Castrop, Hayo, Mack, Matthias
Format:	Journal Article
Language:	English
Published:	United States 01.07.2018
Subjects:	Acute Kidney Injury - etiology Acute Kidney Injury - metabolism Acute Kidney Injury - pathology Acute Kidney Injury - physiopathology Adenine Animals Bone Marrow Cells - metabolism Cell Lineage Collagen Type I - genetics Collagen Type I - metabolism Epithelial Cells - metabolism Female Fibroblasts - metabolism Fibrosis Glomerular Filtration Rate Hematopoiesis Kidney - pathology Kidney - physiopathology Kidney Tubules - cytology Mice Mice, Knockout Renal Insufficiency, Chronic - chemically induced Renal Insufficiency, Chronic - metabolism Renal Insufficiency, Chronic - pathology Renal Insufficiency, Chronic - physiopathology Ureteral Obstruction - complications chronic kidney disease fibrosis interstitial fibrosis chronic renal failure immunology
ISSN:	1533-3450, 1533-3450
Online Access:	Get more information
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