Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer

This article reports the n−3 fatty acid portion of a randomized, placebo-controlled, two-by-two factorial trial of vitamin D and marine n−3 fatty acids in the primary prevention of cancer and cardiovascular disease. Fatty acids did not lead to a lower incidence of major cardiovascular events or canc...

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Bibliographic Details
Published in:The New England journal of medicine Vol. 380; no. 1; pp. 23 - 32
Main Authors: Manson, JoAnn E, Cook, Nancy R, Lee, I-Min, Christen, William, Bassuk, Shari S, Mora, Samia, Gibson, Heike, Albert, Christine M, Gordon, David, Copeland, Trisha, D’Agostino, Denise, Friedenberg, Georgina, Ridge, Claire, Bubes, Vadim, Giovannucci, Edward L, Willett, Walter C, Buring, Julie E
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 03.01.2019
Subjects:
Age
Aged
Cancer
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - mortality
Cardiovascular Diseases - prevention & control
Cerebral infarction
Clinical trials
Death
Diabetes
Dietary supplements
Disease prevention
Drug dosages
Evidence-based medicine
Fatty acids
Fatty Acids, Omega-3 - adverse effects
Fatty Acids, Omega-3 - therapeutic use
FDA approval
Female
Fish oils
Follow-Up Studies
Health risk assessment
Heart attacks
Humans
Hypothesis testing
Incidence
Intervention
Investigations
Male
Middle Aged
Myocardial infarction
Neoplasms - epidemiology
Neoplasms - mortality
Neoplasms - prevention & control
Omega-3 fatty acids
Questionnaires
Stroke
Supplements
Treatment Failure
Vitamin D
Vitamin D3
Womens health
United States > US
ISSN:0028-4793, 1533-4406, 1533-4406
Online Access:Get full text
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Description
Summary:This article reports the n−3 fatty acid portion of a randomized, placebo-controlled, two-by-two factorial trial of vitamin D and marine n−3 fatty acids in the primary prevention of cancer and cardiovascular disease. Fatty acids did not lead to a lower incidence of major cardiovascular events or cancer.
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ObjectType-Evidence Based Healthcare-1
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa1811403