Pralatrexate in patients with relapsed or refractory peripheral T-cell lymphoma: results from the pivotal PROPEL study

Peripheral T-cell lymphoma (PTCL) is a poor prognosis subtype of non-Hodgkin's lymphoma with no accepted standard of care. This study evaluated the efficacy and tolerability of pralatrexate, a novel antifolate with promising activity. Patients with independently confirmed PTCL who progressed fo...

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Veröffentlicht in:	Journal of clinical oncology Jg. 29; H. 9; S. 1182
Hauptverfasser:	O'Connor, Owen A, Pro, Barbara, Pinter-Brown, Lauren, Bartlett, Nancy, Popplewell, Leslie, Coiffier, Bertrand, Lechowicz, Mary Jo, Savage, Kerry J, Shustov, Andrei R, Gisselbrecht, Christian, Jacobsen, Eric, Zinzani, Pier Luigi, Furman, Richard, Goy, Andre, Haioun, Corinne, Crump, Michael, Zain, Jasmine M, Hsi, Eric, Boyd, Adam, Horwitz, Steven
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 20.03.2011
Schlagworte:	Adult Aged Aged, 80 and over Aminopterin - analogs & derivatives Aminopterin - therapeutic use Drug Resistance, Neoplasm - drug effects Female Folic Acid Antagonists - therapeutic use Humans International Agencies Lymphoma, T-Cell, Peripheral - drug therapy Lymphoma, T-Cell, Peripheral - pathology Male Middle Aged Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - pathology Prospective Studies Remission Induction Salvage Therapy Standard of Care Survival Rate Treatment Outcome Young Adult
ISSN:	1527-7755, 1527-7755
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