Pralatrexate in patients with relapsed or refractory peripheral T-cell lymphoma: results from the pivotal PROPEL study

Peripheral T-cell lymphoma (PTCL) is a poor prognosis subtype of non-Hodgkin's lymphoma with no accepted standard of care. This study evaluated the efficacy and tolerability of pralatrexate, a novel antifolate with promising activity. Patients with independently confirmed PTCL who progressed fo...

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Bibliographic Details
Published in:	Journal of clinical oncology Vol. 29; no. 9; p. 1182
Main Authors:	O'Connor, Owen A, Pro, Barbara, Pinter-Brown, Lauren, Bartlett, Nancy, Popplewell, Leslie, Coiffier, Bertrand, Lechowicz, Mary Jo, Savage, Kerry J, Shustov, Andrei R, Gisselbrecht, Christian, Jacobsen, Eric, Zinzani, Pier Luigi, Furman, Richard, Goy, Andre, Haioun, Corinne, Crump, Michael, Zain, Jasmine M, Hsi, Eric, Boyd, Adam, Horwitz, Steven
Format:	Journal Article
Language:	English
Published:	United States 20.03.2011
Subjects:	Adult Aged Aged, 80 and over Aminopterin - analogs & derivatives Aminopterin - therapeutic use Drug Resistance, Neoplasm - drug effects Female Folic Acid Antagonists - therapeutic use Humans International Agencies Lymphoma, T-Cell, Peripheral - drug therapy Lymphoma, T-Cell, Peripheral - pathology Male Middle Aged Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - pathology Prospective Studies Remission Induction Salvage Therapy Standard of Care Survival Rate Treatment Outcome Young Adult
ISSN:	1527-7755, 1527-7755
Online Access:	Get more information
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