Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease

Little is known about the roles of myeloid cell subsets in kidney injury and in the limited ability of the organ to repair itself. Characterizing these cells based only on surface markers using flow cytometry might not provide a full phenotypic picture. Defining these cells at the single-cell, trans...

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Bibliographic Details
Published in:	Journal of the American Society of Nephrology Vol. 31; no. 12; p. 2833
Main Authors:	Conway, Bryan R, O'Sullivan, Eoin D, Cairns, Carolynn, O'Sullivan, James, Simpson, Daniel J, Salzano, Angela, Connor, Katie, Ding, Peng, Humphries, Duncan, Stewart, Kevin, Teenan, Oliver, Pius, Riinu, Henderson, Neil C, Bénézech, Cécile, Ramachandran, Prakash, Ferenbach, David, Hughes, Jeremy, Chandra, Tamir, Denby, Laura
Format:	Journal Article
Language:	English
Published:	United States 01.12.2020
Subjects:	Animals Disease Models, Animal Disease Progression Kidney Diseases - etiology Kidney Diseases - metabolism Kidney Diseases - pathology Macrophages - physiology Male Mice Mice, Inbred C57BL Myeloid Cells - physiology Sequence Analysis, RNA Single-Cell Analysis Ureteral Obstruction - etiology kidney disease fibrosis myeloid cells scRNA sequencing
ISSN:	1533-3450, 1533-3450
Online Access:	Get more information
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