Corneal myofibroblasts and fibrosis

Myofibroblasts are alpha-smooth muscle actin (SMA)+ cells that have a critical role in the corneal stromal response to infections, injuries, and surgeries, and which produce corneal scarring fibrosis when they develop in excess. These contractile and opaque cells—produce large amounts of disordered...

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Bibliographic Details
Published in:	Experimental eye research Vol. 201; p. 108272
Main Author:	Wilson, Steven E.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.12.2020
Subjects:	Animals Cornea Cornea - pathology Corneal Diseases - metabolism Corneal Diseases - pathology Corneal fibroblasts Descemet's membrane Epithelial basement membrane Extracellular Matrix - metabolism Fibroblasts - metabolism Fibroblasts - pathology Fibrocytes Fibrosis Humans Infection Injury Interleukin-1 Myofibroblasts Myofibroblasts - metabolism Myofibroblasts - physiology PDGF Scarring TGF beta Wound healing Cornea Interleukin-1 Wound healing Fibrocytes Injury Infection Descemet's membrane PDGF Fibrosis Epithelial basement membrane Corneal fibroblasts Myofibroblasts TGF beta Scarring
ISSN:	0014-4835, 1096-0007, 1096-0007
Online Access:	Get full text
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