Analyzing In Silico the Relationship Between the Activation of the Edema Factor and Its Interaction With Calmodulin

Molecular dynamics (MD) simulations have been recorded on the complex between the edema factor (EF) of Bacilllus anthracis and calmodulin (CaM), starting from a structure with the orthosteric inhibitor adefovir bound in the EF catalytic site. The starting structure has been destabilized by alternate...

Full description

Saved in:

Bibliographic Details
Published in:	Frontiers in molecular biosciences Vol. 7; p. 586544
Main Authors:	Pitard, Irène, Monet, Damien, Goossens, Pierre L., Blondel, Arnaud, Malliavin, Thérèse E.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media 04.12.2020 Frontiers Media S.A
Subjects:	allostery Bacillus anthracis Biochemistry, Molecular Biology Bioinformatics Biophysics Cavity detection Computer Science Life Sciences Molecular Biosciences protein-protein interaction Structural Biology virulence factor Bacillus anthracis protein-protein interaction virulence factor Cavity detection allostery
ISSN:	2296-889X, 1662-5099, 2296-889X, 1662-5099
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!