Lipids and insulin regulate mitochondrial‐derived peptide (MOTS‐c) in PCOS and healthy subjects

Objective Polycystic ovarian syndrome (PCOS) is a heterogeneous endocrine disorder associated with mitochondrial dysfunction and insulin resistance (IR). MOTS‐c, a mitochondrial peptide, promotes insulin sensitivity (IS) through activating AKT and AMPK‐dependent pathways. The current study was desig...

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Bibliographic Details
Published in:	Clinical endocrinology (Oxford) Vol. 91; no. 2; pp. 278 - 287
Main Authors:	Ramanjaneya, Manjunath, Jerobin, Jayakumar, Bettahi, Ilham, Bensila, Milin, Aye, Myint, Siveen, Kodappully Sivaraman, Sathyapalan, Thozhukat, Skarulis, Monica, Abou‐Samra, Abdul‐Badi, Atkin, Stephen L.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.08.2019
Subjects:	AKT protein Enzyme-linked immunosorbent assay Glucose Insulin Insulin resistance Lipids Metabolic syndrome Mitochondria mitochondrial dysfunction mitochondrial open reading frame of the 12S rRNA type‐c Peptides polycystic ovarian syndrome Polycystic ovary syndrome triglycerides and insulin resistance metabolic syndrome mitochondrial open reading frame of the 12S rRNA type-c mitochondrial dysfunction triglycerides and insulin resistance polycystic ovarian syndrome
ISSN:	0300-0664, 1365-2265, 1365-2265
Online Access:	Get full text
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