The influence of corticosteroids on hemostasis in healthy subjects

Essentials Corticosteroids are associated with venous thromboembolism in patients with inflammatory diseases. Healthy subjects received 0.5 mg kg−1 of prednisolone or placebo for 10 days in a randomized study. von Willebrand factor, plasminogen activator type 1 and in vitro thrombin generation were...

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Bibliographic Details
Published in:	Journal of thrombosis and haemostasis Vol. 14; no. 4; pp. 716 - 723
Main Authors:	Majoor, C. J., Sneeboer, M. M. S., Kievit, A., Meijers, J. C. M., Poll, T., Lutter, R., Bel, E. H., Kamphuisen, P. W.
Format:	Journal Article
Language:	English
Published:	England Elsevier Limited 01.04.2016
Subjects:	Administration, Oral Adrenal Cortex Hormones - adverse effects Adult Blood Coagulation - drug effects corticosteroids Double-Blind Method Female Fibrin Fibrinogen Degradation Products - chemistry fibrinolysis Fibrinolysis - drug effects Health risk assessment Healthy Volunteers hemostasis Hemostasis - drug effects Humans Inflammation - complications Inflammatory diseases Male Plasminogen Activator Inhibitor 1 - blood Prednisolone - adverse effects pulmonary embolism therapy Thrombin - chemistry Thromboembolism Venous Thromboembolism - chemically induced von Willebrand Factor - chemistry Young Adult fibrinolysis hemostasis corticosteroids pulmonary embolism therapy healthy volunteers
ISSN:	1538-7933, 1538-7836, 1538-7836
Online Access:	Get full text
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