Cytoplasmic functions of long noncoding RNAs

Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are closely linked to their interaction with RNA‐binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Wiley interdisciplinary reviews. RNA Ročník 9; číslo 3; s. e1471 - n/a
Hlavní autoři:	Noh, Ji Heon, Kim, Kyoung Mi, McClusky, Waverly G., Abdelmohsen, Kotb, Gorospe, Myriam
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Hoboken, USA John Wiley & Sons, Inc 01.05.2018 Wiley Subscription Services, Inc
Témata:	Animals circRNA Cytoplasm - genetics Gene regulation Humans lncRNA Localization miRNA mRNA stability mRNA turnover noncoding RNA Nucleotides post‐transcriptional gene regulation Protein Stability Protein turnover Proteins ribonucleoprotein complexes Riboswitches RNA Stability RNA transport RNA, Long Noncoding RNA, Messenger RNA-mediated interference Signal Transduction Transcription post-transcriptional gene regulation miRNA lncRNA noncoding RNA circRNA ribonucleoprotein complexes
ISSN:	1757-7004, 1757-7012, 1757-7012
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Abstract	Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are closely linked to their interaction with RNA‐binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA‐centered therapeutic strategies. This article is categorized under: RNA Export and Localization > RNA Localization Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications Different levels of regulation of gene expression by cytoplasmic lncRNAs. Cytoplasmic lncRNAs can (clockwise from top): alter the stability and translation of mRNAs, activate signaling molecules, affect organelle function, modulate the stability of specific proteins, and serve as decoys for cytosolic factors.
AbstractList	Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are closely linked to their interaction with RNA‐binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA‐centered therapeutic strategies. This article is categorized under: RNA Export and Localization > RNA Localization Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications Different levels of regulation of gene expression by cytoplasmic lncRNAs. Cytoplasmic lncRNAs can (clockwise from top): alter the stability and translation of mRNAs, activate signaling molecules, affect organelle function, modulate the stability of specific proteins, and serve as decoys for cytosolic factors. Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are closely linked to their interaction with RNA‐binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA‐centered therapeutic strategies.This article is categorized under:RNA Export and Localization > RNA LocalizationRegulatory RNAs/RNAi/Riboswitches > Regulatory RNAsRNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein-coding function. Their functions are closely linked to their interaction with RNA-binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA-centered therapeutic strategies. This article is categorized under: RNA Export and Localization > RNA Localization Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Interactions with Proteins and Other Molecules > Protein-RNA Interactions: Functional Implications.Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein-coding function. Their functions are closely linked to their interaction with RNA-binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA-centered therapeutic strategies. This article is categorized under: RNA Export and Localization > RNA Localization Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Interactions with Proteins and Other Molecules > Protein-RNA Interactions: Functional Implications. Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are closely linked to their interaction with RNA‐binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA‐centered therapeutic strategies. This article is categorized under: RNA Export and Localization > RNA Localization Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein-coding function. Their functions are closely linked to their interaction with RNA-binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that enable gene organization and control transcription. Cytoplasmic lncRNAs are less well understood, but accumulating evidence indicates that they also form complexes with diverse structural and regulatory functions. Here, we review our current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytoplasmic lncRNA complexes, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways. We conclude by discussing areas of future study needed to elucidate comprehensively the biology of lncRNAs, to further understand the impact of lncRNAs on physiology and design lncRNA-centered therapeutic strategies. This article is categorized under: RNA Export and Localization > RNA Localization Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Interactions with Proteins and Other Molecules > Protein-RNA Interactions: Functional Implications.
Author	McClusky, Waverly G. Abdelmohsen, Kotb Noh, Ji Heon Kim, Kyoung Mi Gorospe, Myriam
Author_xml	– sequence: 1 givenname: Ji Heon surname: Noh fullname: Noh, Ji Heon email: jiheon.noh@nih.gov organization: National Institutes of Health – sequence: 2 givenname: Kyoung Mi surname: Kim fullname: Kim, Kyoung Mi organization: National Institutes of Health – sequence: 3 givenname: Waverly G. surname: McClusky fullname: McClusky, Waverly G. organization: National Institutes of Health – sequence: 4 givenname: Kotb surname: Abdelmohsen fullname: Abdelmohsen, Kotb organization: National Institutes of Health – sequence: 5 givenname: Myriam surname: Gorospe fullname: Gorospe, Myriam organization: National Institutes of Health
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/29516680$$D View this record in MEDLINE/PubMed
BookMark	eNp1kF1LwzAUhoMobs5d-Adk4I2C3XKytGkux_ALhoIoXoY0TSSjbWbTMvbvTd3mxdDc5BCe9z3kOUPHlas0QheAx4AxmazrSo6BMjhCfWAxixgGcvw7Y9pDQ--XOByKCQM4RT3CY0iSFPfR7XzTuFUhfWnVyLSVaqyr_MiZUeGqz1HYpVxuw_T6PPPn6MTIwuvh7h6g9_u7t_ljtHh5eJrPFpGiMYWISOBhcU4SncjuyWTMJJxCDIRqZkwGkDKKJWEkjiElgAnnJMtSxZnOk-kAXW97V7X7arVvRGm90kUhK-1aL0j4YajgaYdeHaBL1wYjRUcRRhOS8mmgLndUm5U6F6valrLeiL2HAEy2gKqd97U2QtlGdi6aWtpCABadbNHJFp3skLg5SOxL_2J37Wtb6M3_oPgIln8S3xF2ioY
CitedBy_id	crossref_primary_10_1186_s12920_020_00834_6 crossref_primary_10_1186_s12864_021_07811_y crossref_primary_10_1093_plcell_koad027 crossref_primary_10_4252_wjsc_v11_i3_167 crossref_primary_10_1038_s41440_020_0408_2 crossref_primary_10_1007_s11033_020_05916_3 crossref_primary_10_3389_fgene_2022_968919 crossref_primary_10_3389_fmolb_2021_724225 crossref_primary_10_1186_s10020_022_00576_4 crossref_primary_10_3390_ijms22041882 crossref_primary_10_1016_j_omtn_2019_11_027 crossref_primary_10_1186_s13046_021_01943_5 crossref_primary_10_1002_1878_0261_12676 crossref_primary_10_1186_s12915_024_01970_6 crossref_primary_10_1002_jcp_29825 crossref_primary_10_1038_s41590_019_0422_1 crossref_primary_10_3389_fonc_2020_628608 crossref_primary_10_1002_jcp_29288 crossref_primary_10_1016_j_bbagrm_2024_195073 crossref_primary_10_3233_NIB_190159 crossref_primary_10_20935_AcadBiol7706 crossref_primary_10_1080_21655979_2020_1863014 crossref_primary_10_1111_jcmm_18068 crossref_primary_10_3389_fphys_2019_00030 crossref_primary_10_1016_j_mad_2020_111243 crossref_primary_10_1002_ctm2_1292 crossref_primary_10_1002_jcb_29206 crossref_primary_10_3389_fendo_2020_610213 crossref_primary_10_3390_ijms241512076 crossref_primary_10_1080_1354750X_2024_2341411 crossref_primary_10_1128_jvi_01782_21 crossref_primary_10_62347_EHQK5961 crossref_primary_10_1002_mc_23199 crossref_primary_10_1002_jcp_27198 crossref_primary_10_3389_fgene_2021_668313 crossref_primary_10_1002_wrna_1625 crossref_primary_10_1016_j_isci_2024_109207 crossref_primary_10_1097_MD_0000000000020722 crossref_primary_10_1038_s41598_019_42162_5 crossref_primary_10_1038_s41598_023_37236_4 crossref_primary_10_1002_jgm_3125 crossref_primary_10_1080_17520363_2025_2529769 crossref_primary_10_1155_2022_5793912 crossref_primary_10_1186_s13619_022_00109_8 crossref_primary_10_2217_epi_2023_0053 crossref_primary_10_1016_j_heliyon_2024_e32245 crossref_primary_10_2217_epi_2021_0163 crossref_primary_10_1242_dev_182741 crossref_primary_10_3389_fgene_2019_00135 crossref_primary_10_3390_cells11121949 crossref_primary_10_1007_s10620_019_05829_7 crossref_primary_10_1016_j_bbcan_2021_188612 crossref_primary_10_3389_fcell_2020_00517 crossref_primary_10_1016_j_semcdb_2020_09_006 crossref_primary_10_1016_j_omtn_2019_11_003 crossref_primary_10_1111_gtc_12997 crossref_primary_10_1007_s11011_024_01456_y crossref_primary_10_1186_s12935_024_03372_8 crossref_primary_10_3389_fgene_2020_00631 crossref_primary_10_1002_wrna_1750 crossref_primary_10_1080_03630269_2023_2284950 crossref_primary_10_1002_wrna_1633 crossref_primary_10_3390_cancers13071555 crossref_primary_10_3390_ncrna7040062 crossref_primary_10_1038_s41419_023_06196_y crossref_primary_10_1177_0963689720906777 crossref_primary_10_1002_glia_24045 crossref_primary_10_1038_s41467_023_40883_w crossref_primary_10_1007_s10142_024_01444_6 crossref_primary_10_1002_jgm_3065 crossref_primary_10_1096_fj_202501630R crossref_primary_10_1016_j_lfs_2020_118579 crossref_primary_10_3389_fcimb_2023_1160198 crossref_primary_10_2174_1381612828666220211153304 crossref_primary_10_3390_ncrna7010003 crossref_primary_10_1186_s12263_024_00739_4 crossref_primary_10_1016_j_fct_2023_113653 crossref_primary_10_1073_pnas_1810729116 crossref_primary_10_1038_s41590_019_0406_1 crossref_primary_10_1111_jcmm_15968 crossref_primary_10_1016_j_lfs_2021_119025 crossref_primary_10_1093_bjd_ljaf108 crossref_primary_10_1002_ijc_32608 crossref_primary_10_3390_cancers15225313 crossref_primary_10_1007_s11033_021_06161_y crossref_primary_10_1016_j_heliyon_2021_e06395 crossref_primary_10_3389_fpls_2018_00873 crossref_primary_10_3389_fgene_2020_00413 crossref_primary_10_1155_2020_8888085 crossref_primary_10_1186_s12935_020_01680_3 crossref_primary_10_3389_fgene_2019_00083 crossref_primary_10_14348_molcells_2022_0056 crossref_primary_10_3389_fgene_2024_1356558 crossref_primary_10_3390_ncrna7010016 crossref_primary_10_1016_j_lfs_2024_122544 crossref_primary_10_1186_s13287_023_03441_1 crossref_primary_10_1093_nar_gkz1149 crossref_primary_10_3892_ijmm_2023_5271 crossref_primary_10_3389_fonc_2021_651693 crossref_primary_10_1016_j_biopha_2020_110359 crossref_primary_10_1016_j_bcp_2025_117174 crossref_primary_10_1038_s41420_023_01544_5 crossref_primary_10_1002_cbin_11634 crossref_primary_10_3389_fcvm_2021_728746 crossref_primary_10_1097_MD_0000000000032318 crossref_primary_10_3390_ncrna5010030 crossref_primary_10_3390_ncrna7020024 crossref_primary_10_1007_s12041_020_01218_6 crossref_primary_10_1093_nar_gkae590 crossref_primary_10_1261_rna_075309_120 crossref_primary_10_1158_0008_5472_CAN_21_4349 crossref_primary_10_1089_cbr_2020_3587 crossref_primary_10_3390_ncrna8020028 crossref_primary_10_1186_s12967_022_03521_5 crossref_primary_10_1093_nar_gkac1174 crossref_primary_10_1111_cpr_12700 crossref_primary_10_1016_j_tranon_2022_101487 crossref_primary_10_1002_jcp_29222 crossref_primary_10_3389_fimmu_2024_1342213 crossref_primary_10_3389_fonc_2022_954634 crossref_primary_10_3390_ijms24032259 crossref_primary_10_1111_jcmm_14974 crossref_primary_10_1038_s41388_021_02073_0 crossref_primary_10_1038_s41420_020_00359_y crossref_primary_10_3390_ncrna11040051 crossref_primary_10_3390_gidisord2030022 crossref_primary_10_3390_cancers17030472 crossref_primary_10_1016_j_humimm_2024_111170 crossref_primary_10_1007_s11523_020_00717_x crossref_primary_10_3389_frnar_2024_1473293 crossref_primary_10_1016_j_biopha_2019_109501 crossref_primary_10_1002_hep_30165 crossref_primary_10_1002_jcla_24406 crossref_primary_10_2217_epi_2021_0212 crossref_primary_10_1016_j_bbamcr_2020_118837 crossref_primary_10_1007_s11010_023_04887_w crossref_primary_10_1631_jzus_B2101052 crossref_primary_10_1007_s11033_022_07364_7 crossref_primary_10_1101_gad_320523_118 crossref_primary_10_1016_j_lfs_2020_117298 crossref_primary_10_1038_s41420_021_00787_4 crossref_primary_10_3390_cancers12123867 crossref_primary_10_3390_ijms23137471 crossref_primary_10_26508_lsa_201900398 crossref_primary_10_1016_j_cmet_2023_06_019 crossref_primary_10_1093_toxsci_kfaa001 crossref_primary_10_1089_hum_2020_106 crossref_primary_10_3390_ncrna6040044 crossref_primary_10_1080_15384101_2023_2172265 crossref_primary_10_3390_ijms222212497 crossref_primary_10_1093_nar_gkaa1151 crossref_primary_10_3233_JAD_180259 crossref_primary_10_1161_ATVBAHA_122_318536 crossref_primary_10_1016_j_ijbiomac_2023_127341 crossref_primary_10_3233_JAD_230057 crossref_primary_10_1016_j_molcel_2019_02_008 crossref_primary_10_1186_s12885_022_10186_2 crossref_primary_10_1186_s12935_020_01565_5 crossref_primary_10_1038_s41569_023_00952_5 crossref_primary_10_1038_s41419_021_03690_z crossref_primary_10_1016_j_ijbiomac_2022_08_018 crossref_primary_10_1186_s13046_022_02257_w crossref_primary_10_1007_s00018_020_03554_3 crossref_primary_10_1002_jcp_29315 crossref_primary_10_1016_j_csbj_2024_11_015 crossref_primary_10_3389_fonc_2022_950783 crossref_primary_10_1371_journal_ppat_1010600 crossref_primary_10_1007_s00705_025_06335_0 crossref_primary_10_1177_15330338211038488 crossref_primary_10_3389_fendo_2021_665811 crossref_primary_10_3390_genes13122381 crossref_primary_10_1007_s12094_022_02848_1 crossref_primary_10_3390_ijms24032605 crossref_primary_10_1093_nar_gky860 crossref_primary_10_3390_ijms23020764 crossref_primary_10_1016_j_dld_2022_02_011 crossref_primary_10_1016_j_gene_2021_145803 crossref_primary_10_4049_jimmunol_2100602 crossref_primary_10_1016_j_mbplus_2021_100060 crossref_primary_10_3390_cancers14122819 crossref_primary_10_1186_s12915_024_02069_8 crossref_primary_10_1002_cam4_2859 crossref_primary_10_1016_j_intimp_2024_113309 crossref_primary_10_1111_exd_70054 crossref_primary_10_1186_s12859_021_04207_3 crossref_primary_10_1002_cam4_3703 crossref_primary_10_1002_stem_3130 crossref_primary_10_3389_fonc_2022_850943 crossref_primary_10_1111_cns_14277 crossref_primary_10_1038_s41420_021_00500_5 crossref_primary_10_3389_fphar_2019_00539 crossref_primary_10_3390_ijms251910316 crossref_primary_10_3389_fgene_2023_1056000 crossref_primary_10_3390_ijms241411677 crossref_primary_10_3390_ijms22094365 crossref_primary_10_1101_gad_351557_124 crossref_primary_10_1093_jb_mvaa082 crossref_primary_10_1186_s13046_019_1482_7 crossref_primary_10_1007_s12013_024_01441_3 crossref_primary_10_1007_s12094_022_02982_w crossref_primary_10_1002_mc_23126 crossref_primary_10_3390_epigenomes2020009 crossref_primary_10_1002_jcp_29871 crossref_primary_10_1016_j_ijbiomac_2024_133814 crossref_primary_10_1016_j_ijbiomac_2024_130426 crossref_primary_10_1016_j_vph_2019_02_004 crossref_primary_10_3748_wjg_v29_i33_4927 crossref_primary_10_1002_wrna_1647 crossref_primary_10_3389_fnmol_2019_00165 crossref_primary_10_3389_fonc_2021_749753 crossref_primary_10_1016_j_yexmp_2020_104518 crossref_primary_10_1038_s41598_024_59494_6 crossref_primary_10_1186_s12864_021_07478_5 crossref_primary_10_1038_s41419_022_05270_1 crossref_primary_10_1186_s12872_025_04590_2 crossref_primary_10_1186_s13046_020_01561_7 crossref_primary_10_1080_15384101_2022_2099191 crossref_primary_10_2174_1574893618666230223143914 crossref_primary_10_3390_ijms26020676 crossref_primary_10_1016_j_exger_2020_110889 crossref_primary_10_1002_wrna_1778 crossref_primary_10_3390_ijms24043531 crossref_primary_10_3390_ncrna9050048 crossref_primary_10_1016_j_ygeno_2021_12_020 crossref_primary_10_2147_IJGM_S342611 crossref_primary_10_1111_jcmm_17069 crossref_primary_10_1186_s12885_021_08923_0 crossref_primary_10_1002_iid3_1066 crossref_primary_10_1080_21655979_2021_1972784 crossref_primary_10_1007_s11064_021_03436_5 crossref_primary_10_3390_ijms20081938 crossref_primary_10_1186_s13058_023_01709_1 crossref_primary_10_1007_s10735_021_09969_x crossref_primary_10_1093_icb_icaf040 crossref_primary_10_1007_s10522_025_10312_0 crossref_primary_10_1016_j_ijbiomac_2025_141817 crossref_primary_10_1002_adhm_202002070 crossref_primary_10_1016_j_isci_2025_113070 crossref_primary_10_1111_jnc_15198 crossref_primary_10_1038_s41419_021_03453_w crossref_primary_10_1007_s11064_022_03613_0 crossref_primary_10_3390_biom11111673 crossref_primary_10_3389_fgene_2024_1478352 crossref_primary_10_1186_s12935_020_01306_8 crossref_primary_10_2217_epi_2022_0432 crossref_primary_10_1007_s10528_022_10313_5 crossref_primary_10_1016_j_virusres_2018_08_018 crossref_primary_10_1007_s13577_021_00636_7 crossref_primary_10_1016_j_molcel_2021_11_032 crossref_primary_10_1080_15548627_2019_1598750 crossref_primary_10_3390_cells10061407 crossref_primary_10_1186_s12915_024_02032_7 crossref_primary_10_3389_fphar_2022_952061 crossref_primary_10_3389_fgene_2021_733925 crossref_primary_10_1016_j_cpt_2022_12_003 crossref_primary_10_1074_jbc_RA120_015775 crossref_primary_10_1139_bcb_2019_0497 crossref_primary_10_1038_s41418_019_0467_6 crossref_primary_10_7717_peerj_9292 crossref_primary_10_1038_s41598_019_40094_8 crossref_primary_10_1158_1541_7786_MCR_22_0009 crossref_primary_10_1177_0960327120979032 crossref_primary_10_1080_15384047_2023_2165896 crossref_primary_10_1016_j_ncrna_2025_04_008 crossref_primary_10_2147_OTT_S297209 crossref_primary_10_3390_ijms24054796 crossref_primary_10_1016_j_cca_2022_05_030 crossref_primary_10_3390_nu13092952
Cites_doi	10.1016/j.cell.2010.03.009 10.1261/rna.044560.114 10.1002/wrna.1168 10.18632/aging.100710 10.1016/j.febslet.2013.07.048 10.1016/j.cell.2010.06.035 10.1038/ng.710 10.1261/rna.053561.115 10.1038/ng.848 10.1093/database/baw035 10.1101/gad.269803.115 10.1016/j.molcel.2012.06.027 10.1080/15476286.2017.1279788 10.1126/science.1112014 10.1073/pnas.1415098111 10.1038/emboj.2012.292 10.1073/pnas.0804283105 10.1073/pnas.85.23.8800 10.1016/j.ymeth.2013.07.030 10.1126/science.1231776 10.1016/j.cell.2016.02.054 10.1038/ncomms3939 10.1038/nature07488 10.1038/nn.2778 10.1038/srep24922 10.1038/nsmb.1838 10.1038/nature11508 10.1038/srep12453 10.1126/science.1163045 10.1186/s12864-015-1273-2 10.1016/j.yjmcc.2015.01.011 10.1038/ncomms11730 10.1016/j.cell.2011.10.002 10.1038/nature11661 10.1016/j.jmb.2012.11.024 10.1016/j.gpb.2016.03.005 10.1016/j.bbagrm.2015.06.010 10.1186/gb-2014-15-1-r6 10.1038/nsmb.2480 10.1371/journal.pone.0107016 10.1089/dna.2015.3187 10.1039/C4MB00409D 10.1016/j.cell.2013.02.012 10.1093/nar/gku686 10.1038/ncb3295 10.1016/j.molcel.2017.04.008 10.1093/nar/24.9.1589 10.1016/j.celrep.2014.04.050 10.1089/dna.2017.3678 10.1016/j.celrep.2014.07.045 10.1093/nar/gks658 10.1038/nn.2779 10.1093/nar/gks997 10.1016/j.cell.2011.09.028 10.1038/nm1784 10.1038/srep28087 10.1126/science.aam9321 10.1038/nrg3813 10.1093/nar/gkw017 10.1126/science.aaf5573 10.1371/journal.pgen.1003569 10.7554/eLife.00762 10.1126/science.1115901 10.1586/14737159.4.3.317 10.1016/j.molcel.2013.08.027 10.1016/j.cell.2011.11.055 10.1091/mbc.E02-11-0757 10.1016/j.molcel.2009.01.026 10.1016/j.devcel.2015.05.009 10.1016/j.cell.2010.06.040 10.1016/j.devcel.2013.03.002 10.1038/cddis.2013.541 10.1038/ncomms12209 10.1038/nature12311 10.1371/journal.pone.0167851 10.1042/BCJ20170280 10.1101/gr.132159.111 10.1083/jcb.201108113 10.1016/j.bbagen.2013.10.035 10.18632/oncotarget.17219 10.1038/nature12756 10.1182/blood-2017-06-788695 10.7554/eLife.16950 10.1261/rna.351707 10.1046/j.1365-2443.1999.00292.x 10.1002/embj.201488411 10.1186/gb-2012-13-11-r107 10.1111/febs.13679 10.1038/nature11993 10.1093/bioinformatics/btu325 10.1016/j.ccell.2015.02.004 10.1038/nrg3049 10.1016/j.molcel.2014.04.025 10.1038/299691a0 10.1016/j.tcb.2010.03.006 10.1002/wrna.1399 10.1038/nrg3141 10.7554/eLife.03523 10.1002/cbin.10301 10.1038/emboj.2013.188 10.1038/ni.2887 10.1172/JCI84419 10.1016/j.bbagrm.2015.07.007 10.1093/nar/gkw1201 10.1016/j.cell.2015.12.017 10.1186/gb-2010-11-5-r56 10.1074/jbc.M806209200 10.1016/j.cell.2013.06.009 10.1093/nar/gkq1069 10.1038/nm.4130 10.1016/j.tibs.2011.12.003 10.1038/nature02342 10.1038/nature09701 10.1093/hmg/10.8.807 10.1371/journal.pbio.0040210 10.1261/rna.029405.111 10.1093/nar/gkq285 10.1371/journal.pgen.1003368 10.1038/nature10887 10.1016/j.cell.2011.06.051 10.1038/onc.2008.373 10.3390/ijms17010132 10.1016/j.molcel.2013.12.012 10.1016/j.ccell.2016.03.010 10.2741/2727 10.1038/ni.3771 10.1158/1078-0432.CCR-06-0134 10.1101/gad.276022.115 10.1038/nature08980 10.1038/nature14234 10.1124/mol.110.064055 10.1186/s40478-016-0316-5 10.1038/nature11928 10.1126/science.1251456 10.1016/j.molcel.2013.11.004 10.1186/s13059-015-0586-4
ContentType	Journal Article
Copyright	Published 2018. This article is a U.S. Government work and is in the public domain in the USA. 2018 Wiley Periodicals, Inc.
Copyright_xml	– notice: Published 2018. This article is a U.S. Government work and is in the public domain in the USA. – notice: 2018 Wiley Periodicals, Inc.
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 7TM 7X8
DOI	10.1002/wrna.1471
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Nucleic Acids Abstracts MEDLINE - Academic
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nucleic Acids Abstracts MEDLINE - Academic
DatabaseTitleList	Nucleic Acids Abstracts MEDLINE - Academic CrossRef MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Anatomy & Physiology
EISSN	1757-7012
EndPage	n/a
ExternalDocumentID	29516680 10_1002_wrna_1471 WRNA1471
Genre	reviewArticle Journal Article Research Support, N.I.H., Intramural Review
GrantInformation_xml	– fundername: National Institute on Aging Intramural Research Program, National Institutes of Health – fundername: Intramural NIH HHS grantid: ZIA AG000511 – fundername: Intramural NIH HHS grantid: Z99 AG999999
GroupedDBID	--- 05W 0R~ 1OC 1VH 31~ 33P 4.4 53G 5DZ 8-0 8-1 A00 AAESR AAHHS AAHQN AAMNL AANHP AANLZ AASGY AAXRX AAYCA AAZKR ABCUV ACAHQ ACBWZ ACCFJ ACCZN ACGFO ACGFS ACPOU ACPRK ACRPL ACXBN ACXQS ACYXJ ADBBV ADEOM ADKYN ADNMO ADOZA ADXAS ADZMN AEEZP AEGXH AEIGN AEQDE AEUYR AFBPY AFFPM AFGKR AFPWT AFZJQ AHBTC AIAGR AITYG AIURR AIWBW AJBDE AJXKR ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMYDB ASPBG AUFTA AVWKF AZFZN AZVAB BDRZF BFHJK BHBCM BMNLL BMXJE BRXPI D-A DCZOG DRFUL DRSTM EBD EBS EJD EMOBN FEDTE G-S GODZA HGLYW HVGLF HZ~ LATKE LEEKS LITHE LOXES LUTES LYRES MEWTI MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM MY. MY~ O66 O9- P2W ROL SUPJJ SV3 WBKPD WHWMO WIH WIK WOHZO WVDHM WXSBR WYJ ZZTAW ~S- AAYXX AEYWJ AGHNM AGQPQ AGYGG CITATION LH4 CGR CUY CVF ECM EIF NPM 7TM 7X8
ID	FETCH-LOGICAL-c4541-2a19700d26e6ac454fb7f69415124e7ffb118740a27255182102992bb8c97ed63
IEDL.DBID	DRFUL
ISICitedReferencesCount	345
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000430472400007&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1757-7004 1757-7012
IngestDate	Sun Nov 09 11:29:29 EST 2025 Sun Jul 13 03:23:36 EDT 2025 Mon Jul 21 06:05:41 EDT 2025 Sat Nov 29 05:51:51 EST 2025 Tue Nov 18 20:58:04 EST 2025 Wed Jan 22 16:49:12 EST 2025
IsDoiOpenAccess	false
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	3
Keywords	post-transcriptional gene regulation miRNA lncRNA noncoding RNA circRNA ribonucleoprotein complexes
Language	English
License	http://onlinelibrary.wiley.com/termsAndConditions#vor Published 2018. This article is a U.S. Government work and is in the public domain in the USA.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c4541-2a19700d26e6ac454fb7f69415124e7ffb118740a27255182102992bb8c97ed63
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
OpenAccessLink	https://www.ncbi.nlm.nih.gov/pmc/articles/5963534
PMID	29516680
PQID	2027462893
PQPubID	2034619
PageCount	15
ParticipantIDs	proquest_miscellaneous_2012118986 proquest_journals_2027462893 pubmed_primary_29516680 crossref_citationtrail_10_1002_wrna_1471 crossref_primary_10_1002_wrna_1471 wiley_primary_10_1002_wrna_1471_WRNA1471
PublicationCentury	2000
PublicationDate	May/June 2018
PublicationDateYYYYMMDD	2018-05-01
PublicationDate_xml	– month: 05 year: 2018 text: May/June 2018
PublicationDecade	2010
PublicationPlace	Hoboken, USA
PublicationPlace_xml	– name: Hoboken, USA – name: United States – name: Oxford
PublicationTitle	Wiley interdisciplinary reviews. RNA
PublicationTitleAlternate	Wiley Interdiscip Rev RNA
PublicationYear	2018
Publisher	John Wiley & Sons, Inc Wiley Subscription Services, Inc
Publisher_xml	– name: John Wiley & Sons, Inc – name: Wiley Subscription Services, Inc
References	e_1_2_12_2_116_1 e_1_2_12_2_7_1 e_1_2_12_2_51_1 e_1_2_12_2_97_1 e_1_2_12_2_32_1 e_1_2_12_2_74_1 e_1_2_12_2_93_1 e_1_2_12_2_70_1 e_1_2_12_2_112_1 e_1_2_12_2_135_1 e_1_2_12_2_3_1 e_1_2_12_2_13_1 e_1_2_12_2_59_1 e_1_2_12_2_17_1 e_1_2_12_2_55_1 e_1_2_12_2_131_1 e_1_2_12_2_36_1 e_1_2_12_2_78_1 e_1_2_12_2_109_1 e_1_2_12_2_128_1 e_1_2_12_2_105_1 e_1_2_12_2_40_1 e_1_2_12_2_63_1 e_1_2_12_2_86_1 e_1_2_12_2_21_1 e_1_2_12_2_82_1 e_1_2_12_2_25_1 e_1_2_12_2_48_1 e_1_2_12_2_124_1 e_1_2_12_2_101_1 e_1_2_12_2_29_1 e_1_2_12_2_44_1 e_1_2_12_2_67_1 e_1_2_12_2_120_1 e_1_2_12_2_8_1 e_1_2_12_1_2_1 e_1_2_12_2_117_1 e_1_2_12_2_4_1 e_1_2_12_2_136_1 e_1_2_12_2_52_1 e_1_2_12_2_75_1 e_1_2_12_2_98_1 e_1_2_12_2_10_1 e_1_2_12_2_71_1 e_1_2_12_2_94_1 e_1_2_12_2_14_1 e_1_2_12_2_37_1 e_1_2_12_2_113_1 e_1_2_12_2_132_1 e_1_2_12_2_18_1 e_1_2_12_2_33_1 e_1_2_12_2_56_1 e_1_2_12_2_79_1 e_1_2_12_2_129_1 e_1_2_12_2_106_1 e_1_2_12_2_125_1 e_1_2_12_2_90_1 e_1_2_12_2_41_1 e_1_2_12_2_87_1 e_1_2_12_2_64_1 e_1_2_12_2_83_1 e_1_2_12_2_60_1 e_1_2_12_2_49_1 e_1_2_12_2_102_1 e_1_2_12_2_121_1 e_1_2_12_2_22_1 e_1_2_12_2_45_1 e_1_2_12_2_26_1 e_1_2_12_2_68_1 Essers P. B. (e_1_2_12_2_28_1) 2015; 2211 e_1_2_12_2_118_1 e_1_2_12_2_9_1 e_1_2_12_2_19_1 e_1_2_12_2_114_1 e_1_2_12_2_137_1 e_1_2_12_2_5_1 e_1_2_12_2_30_1 e_1_2_12_2_76_1 e_1_2_12_2_53_1 e_1_2_12_2_95_1 e_1_2_12_2_72_1 e_1_2_12_2_91_1 e_1_2_12_2_38_1 e_1_2_12_2_110_1 e_1_2_12_2_133_1 e_1_2_12_2_11_1 e_1_2_12_2_34_1 e_1_2_12_2_15_1 e_1_2_12_2_57_1 e_1_2_12_2_99_1 e_1_2_12_2_107_1 e_1_2_12_2_103_1 e_1_2_12_2_126_1 e_1_2_12_2_42_1 e_1_2_12_2_65_1 e_1_2_12_2_84_1 e_1_2_12_2_61_1 e_1_2_12_2_80_1 e_1_2_12_2_23_1 e_1_2_12_2_122_1 e_1_2_12_2_27_1 e_1_2_12_2_46_1 e_1_2_12_2_69_1 e_1_2_12_2_88_1 e_1_2_12_2_119_1 e_1_2_12_2_6_1 e_1_2_12_2_138_1 e_1_2_12_2_115_1 e_1_2_12_2_31_1 e_1_2_12_2_54_1 e_1_2_12_2_73_1 e_1_2_12_2_96_1 e_1_2_12_2_50_1 e_1_2_12_2_92_1 e_1_2_12_2_2_1 e_1_2_12_2_134_1 e_1_2_12_2_12_1 e_1_2_12_2_39_1 e_1_2_12_2_111_1 e_1_2_12_2_130_1 e_1_2_12_2_16_1 e_1_2_12_2_35_1 e_1_2_12_2_58_1 e_1_2_12_2_77_1 e_1_2_12_2_108_1 e_1_2_12_2_104_1 e_1_2_12_2_127_1 e_1_2_12_2_62_1 e_1_2_12_2_43_1 e_1_2_12_2_85_1 e_1_2_12_2_20_1 e_1_2_12_2_81_1 e_1_2_12_2_100_1 e_1_2_12_2_123_1 e_1_2_12_2_24_1 e_1_2_12_2_66_1 e_1_2_12_2_47_1 e_1_2_12_2_89_1
References_xml	– ident: e_1_2_12_2_47_1 doi: 10.1016/j.cell.2010.03.009 – ident: e_1_2_12_2_59_1 doi: 10.1261/rna.044560.114 – ident: e_1_2_12_2_98_1 doi: 10.1002/wrna.1168 – ident: e_1_2_12_2_41_1 doi: 10.18632/aging.100710 – ident: e_1_2_12_2_131_1 doi: 10.1016/j.febslet.2013.07.048 – ident: e_1_2_12_2_119_1 doi: 10.1016/j.cell.2010.06.035 – ident: e_1_2_12_2_84_1 doi: 10.1038/ng.710 – ident: e_1_2_12_2_15_1 doi: 10.1261/rna.053561.115 – ident: e_1_2_12_2_55_1 doi: 10.1038/ng.848 – ident: e_1_2_12_2_36_1 doi: 10.1093/database/baw035 – ident: e_1_2_12_2_128_1 doi: 10.1101/gad.269803.115 – ident: e_1_2_12_2_136_1 doi: 10.1016/j.molcel.2012.06.027 – ident: e_1_2_12_2_3_1 doi: 10.1080/15476286.2017.1279788 – ident: e_1_2_12_2_16_1 doi: 10.1126/science.1112014 – ident: e_1_2_12_2_35_1 doi: 10.1073/pnas.1415098111 – ident: e_1_2_12_2_83_1 doi: 10.1038/emboj.2012.292 – ident: e_1_2_12_2_106_1 doi: 10.1073/pnas.0804283105 – ident: e_1_2_12_2_32_1 doi: 10.1073/pnas.85.23.8800 – ident: e_1_2_12_2_94_1 doi: 10.1016/j.ymeth.2013.07.030 – ident: e_1_2_12_2_73_1 doi: 10.1126/science.1231776 – ident: e_1_2_12_2_91_1 doi: 10.1016/j.cell.2016.02.054 – ident: e_1_2_12_2_135_1 doi: 10.1038/ncomms3939 – ident: e_1_2_12_2_79_1 doi: 10.1038/nature07488 – ident: e_1_2_12_2_112_1 doi: 10.1038/nn.2778 – ident: e_1_2_12_2_5_1 doi: 10.1038/srep24922 – ident: e_1_2_12_2_70_1 doi: 10.1038/nsmb.1838 – ident: e_1_2_12_2_17_1 doi: 10.1038/nature11508 – ident: e_1_2_12_2_129_1 doi: 10.1038/srep12453 – ident: e_1_2_12_2_138_1 doi: 10.1126/science.1163045 – ident: e_1_2_12_2_133_1 doi: 10.1186/s12864-015-1273-2 – ident: e_1_2_12_2_42_1 doi: 10.1016/j.yjmcc.2015.01.011 – ident: e_1_2_12_2_76_1 doi: 10.1038/ncomms11730 – ident: e_1_2_12_2_57_1 doi: 10.1016/j.cell.2011.10.002 – ident: e_1_2_12_2_71_1 doi: 10.1038/nature11661 – ident: e_1_2_12_2_134_1 doi: 10.1016/j.jmb.2012.11.024 – ident: e_1_2_12_2_103_1 doi: 10.1016/j.gpb.2016.03.005 – ident: e_1_2_12_2_7_1 doi: 10.1016/j.bbagrm.2015.06.010 – ident: e_1_2_12_2_116_1 doi: 10.1186/gb-2014-15-1-r6 – ident: e_1_2_12_2_86_1 doi: 10.1038/nsmb.2480 – ident: e_1_2_12_2_52_1 doi: 10.1371/journal.pone.0107016 – ident: e_1_2_12_2_77_1 doi: 10.1089/dna.2015.3187 – ident: e_1_2_12_2_109_1 doi: 10.1039/C4MB00409D – ident: e_1_2_12_2_9_1 doi: 10.1016/j.cell.2013.02.012 – ident: e_1_2_12_2_2_1 doi: 10.1093/nar/gku686 – ident: e_1_2_12_2_80_1 doi: 10.1038/ncb3295 – ident: e_1_2_12_2_26_1 doi: 10.1016/j.molcel.2017.04.008 – ident: e_1_2_12_2_51_1 doi: 10.1093/nar/24.9.1589 – ident: e_1_2_12_2_63_1 doi: 10.1016/j.celrep.2014.04.050 – ident: e_1_2_12_2_78_1 doi: 10.1089/dna.2017.3678 – ident: e_1_2_12_2_56_1 doi: 10.1016/j.celrep.2014.07.045 – ident: e_1_2_12_2_93_1 doi: 10.1093/nar/gks658 – ident: e_1_2_12_2_100_1 doi: 10.1038/nn.2779 – ident: e_1_2_12_2_37_1 doi: 10.1093/nar/gks997 – ident: e_1_2_12_2_18_1 doi: 10.1016/j.cell.2011.09.028 – ident: e_1_2_12_2_29_1 doi: 10.1038/nm1784 – ident: e_1_2_12_2_44_1 doi: 10.1038/srep28087 – ident: e_1_2_12_2_40_1 doi: 10.1126/science.aam9321 – ident: e_1_2_12_2_33_1 doi: 10.1038/nrg3813 – ident: e_1_2_12_2_67_1 doi: 10.1093/nar/gkw017 – ident: e_1_2_12_2_4_1 doi: 10.1126/science.aaf5573 – ident: e_1_2_12_2_49_1 doi: 10.1371/journal.pgen.1003569 – ident: e_1_2_12_2_102_1 doi: 10.7554/eLife.00762 – ident: e_1_2_12_2_127_1 doi: 10.1126/science.1115901 – ident: e_1_2_12_2_30_1 doi: 10.1586/14737159.4.3.317 – ident: e_1_2_12_2_62_1 doi: 10.1016/j.molcel.2013.08.027 – ident: e_1_2_12_2_115_1 doi: 10.1016/j.cell.2011.11.055 – ident: e_1_2_12_2_137_1 doi: 10.1091/mbc.E02-11-0757 – ident: e_1_2_12_2_21_1 doi: 10.1016/j.molcel.2009.01.026 – ident: e_1_2_12_2_38_1 doi: 10.1016/j.devcel.2015.05.009 – ident: e_1_2_12_2_54_1 doi: 10.1016/j.cell.2010.06.040 – ident: e_1_2_12_2_125_1 doi: 10.1016/j.devcel.2013.03.002 – ident: e_1_2_12_2_53_1 doi: 10.1038/cddis.2013.541 – ident: e_1_2_12_2_111_1 doi: 10.1038/ncomms12209 – ident: e_1_2_12_2_105_1 doi: 10.1038/nature12311 – ident: e_1_2_12_2_110_1 doi: 10.1371/journal.pone.0167851 – ident: e_1_2_12_1_2_1 doi: 10.1042/BCJ20170280 – ident: e_1_2_12_2_23_1 doi: 10.1101/gr.132159.111 – ident: e_1_2_12_2_104_1 doi: 10.1083/jcb.201108113 – ident: e_1_2_12_2_60_1 doi: 10.1016/j.bbagen.2013.10.035 – ident: e_1_2_12_2_68_1 doi: 10.18632/oncotarget.17219 – ident: e_1_2_12_2_25_1 doi: 10.1038/nature12756 – ident: e_1_2_12_2_6_1 doi: 10.1182/blood-2017-06-788695 – ident: e_1_2_12_2_58_1 doi: 10.7554/eLife.16950 – ident: e_1_2_12_2_14_1 doi: 10.1261/rna.351707 – ident: e_1_2_12_2_64_1 doi: 10.1046/j.1365-2443.1999.00292.x – ident: e_1_2_12_2_10_1 doi: 10.1002/embj.201488411 – ident: e_1_2_12_2_65_1 doi: 10.1186/gb-2012-13-11-r107 – ident: e_1_2_12_2_88_1 doi: 10.1111/febs.13679 – ident: e_1_2_12_2_50_1 doi: 10.1038/nature11993 – ident: e_1_2_12_2_99_1 doi: 10.1093/bioinformatics/btu325 – ident: e_1_2_12_2_81_1 doi: 10.1016/j.ccell.2015.02.004 – ident: e_1_2_12_2_118_1 doi: 10.1038/nrg3049 – ident: e_1_2_12_2_24_1 doi: 10.1016/j.molcel.2014.04.025 – ident: e_1_2_12_2_117_1 doi: 10.1038/299691a0 – ident: e_1_2_12_2_126_1 doi: 10.1016/j.tcb.2010.03.006 – ident: e_1_2_12_2_121_1 doi: 10.1002/wrna.1399 – ident: e_1_2_12_2_69_1 doi: 10.1038/nrg3141 – ident: e_1_2_12_2_107_1 doi: 10.7554/eLife.03523 – ident: e_1_2_12_2_34_1 doi: 10.1002/cbin.10301 – ident: e_1_2_12_2_43_1 doi: 10.1038/emboj.2013.188 – ident: e_1_2_12_2_114_1 doi: 10.1038/ni.2887 – ident: e_1_2_12_2_8_1 doi: 10.1172/JCI84419 – ident: e_1_2_12_2_27_1 doi: 10.1016/j.bbagrm.2015.07.007 – ident: e_1_2_12_2_96_1 doi: 10.1093/nar/gkw1201 – ident: e_1_2_12_2_74_1 doi: 10.1016/j.cell.2015.12.017 – ident: e_1_2_12_2_31_1 doi: 10.1186/gb-2010-11-5-r56 – volume: 2211 start-page: 1247 year: 2015 ident: e_1_2_12_2_28_1 article-title: A long noncoding RNA on the ribosome is required for lifespan extension publication-title: Cell Reports – ident: e_1_2_12_2_11_1 doi: 10.1074/jbc.M806209200 – ident: e_1_2_12_2_46_1 doi: 10.1016/j.cell.2013.06.009 – ident: e_1_2_12_2_22_1 doi: 10.1093/nar/gkq1069 – ident: e_1_2_12_2_123_1 doi: 10.1038/nm.4130 – ident: e_1_2_12_2_72_1 doi: 10.1016/j.tibs.2011.12.003 – ident: e_1_2_12_2_48_1 doi: 10.1038/nature02342 – ident: e_1_2_12_2_39_1 doi: 10.1038/nature09701 – ident: e_1_2_12_2_61_1 doi: 10.1093/hmg/10.8.807 – ident: e_1_2_12_2_20_1 doi: 10.1371/journal.pbio.0040210 – ident: e_1_2_12_2_97_1 doi: 10.1093/bioinformatics/btu325 – ident: e_1_2_12_2_101_1 doi: 10.1261/rna.029405.111 – ident: e_1_2_12_2_120_1 doi: 10.1093/nar/gkq285 – ident: e_1_2_12_2_113_1 doi: 10.1371/journal.pgen.1003368 – ident: e_1_2_12_2_45_1 doi: 10.1038/nature10887 – ident: e_1_2_12_2_87_1 doi: 10.1016/j.cell.2011.06.051 – ident: e_1_2_12_2_90_1 doi: 10.1038/onc.2008.373 – ident: e_1_2_12_2_130_1 doi: 10.3390/ijms17010132 – ident: e_1_2_12_2_75_1 doi: 10.1016/j.molcel.2013.12.012 – ident: e_1_2_12_2_108_1 doi: 10.1016/j.ccell.2016.03.010 – ident: e_1_2_12_2_12_1 doi: 10.2741/2727 – ident: e_1_2_12_2_19_1 doi: 10.1038/ni.3771 – ident: e_1_2_12_2_124_1 doi: 10.1158/1078-0432.CCR-06-0134 – ident: e_1_2_12_2_92_1 doi: 10.1101/gad.276022.115 – ident: e_1_2_12_2_66_1 doi: 10.1038/nature08980 – ident: e_1_2_12_2_82_1 doi: 10.1038/nature14234 – ident: e_1_2_12_2_89_1 doi: 10.1124/mol.110.064055 – ident: e_1_2_12_2_95_1 doi: 10.1186/s40478-016-0316-5 – ident: e_1_2_12_2_85_1 doi: 10.1038/nature11928 – ident: e_1_2_12_2_122_1 doi: 10.1126/science.1251456 – ident: e_1_2_12_2_132_1 doi: 10.1016/j.molcel.2013.11.004 – ident: e_1_2_12_2_13_1 doi: 10.1186/s13059-015-0586-4
SSID	ssj0000402711
Score	2.6108723
SecondaryResourceType	review_article
Snippet	Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are... Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein-coding function. Their functions are...
SourceID	proquest pubmed crossref wiley
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	e1471
SubjectTerms	Animals circRNA Cytoplasm - genetics Gene regulation Humans lncRNA Localization miRNA mRNA stability mRNA turnover noncoding RNA Nucleotides post‐transcriptional gene regulation Protein Stability Protein turnover Proteins ribonucleoprotein complexes Riboswitches RNA Stability RNA transport RNA, Long Noncoding RNA, Messenger RNA-mediated interference Signal Transduction Transcription
Title	Cytoplasmic functions of long noncoding RNAs
URI	https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fwrna.1471 https://www.ncbi.nlm.nih.gov/pubmed/29516680 https://www.proquest.com/docview/2027462893 https://www.proquest.com/docview/2012118986
Volume	9
WOSCitedRecordID	wos000430472400007&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVWIB databaseName: Wiley Online Library Full Collection 2020 customDbUrl: eissn: 1757-7012 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000402711 issn: 1757-7004 databaseCode: DRFUL dateStart: 20100101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3dS-NAEB9q9cGX87T30dOTVeS4hws2m2Q_8KmoxQcpIhb7Fjab3UPQRGxV_O9vJkkj5e5A8C0kE2aZj8zsZOc3AAdRlEeGcx2ENrG4QUlEkOVRGORqECUO8wlRo-ufy_FYTaf6ogNHi16YGh-iLbiRZ1Tfa3Jwk80OX0FDn1HS6OfUP77K0W6TLqyeXI4m522JBe2Ty2oCL8ZIGRCQ-wJbaMAP2_eXI9JfaeZy1lqFndHGuxb8ET402SYb1uaxCR1XbEFvWOBO--6F_WDV-c-qsN6DX8cv8_Iek-m7G8so3FUWyUrPbsviNyvKwpYU6NjleDj7BJPR6dXxWdDMUghsnMRhwE2oUQA5F04YuuUz6amJFQN-7KT3WVhN5zNccgJpo52g1jzLlNXS5SL6DF1k5L4CI8ScPNdGOx_G3lrtrDBSeW-Ei2Mb9uHnQp6pbYDGad7FbVpDJPOUJJGSJPqw35Le1-ga_yLaWSglbRxsllLNhtpqddSHvfYxugb97zCFKx-JhvDrlFaiD19qZbZcOGaWQqgBLrbS2f_Zp9coVrr49nbSbVhH5qo-GLkD3fnDo_sOa_ZpfjN72IUVOVW7jbX-AS7F6eI
linkProvider	Wiley-Blackwell
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3dS8NADA-igr74_TGdeoqID5at1-7aA1-GOibOIaLoW2mvdzLY2uGm4n9v0nYVUUHwrbQpOfLR5NLLLwCHjhM7IefSslVD4QalIawodmwr9utOQ2M-IXJ0_Y7X7fqPj_JmCk4nvTA5PkRZcCPPyL7X5OBUkK59ooa-oajR0amBfMZFM0L7njm_bd13yhoLGij3shG8GCQ9i5DcJ-BCdV4r3_8akr7lmV_T1izutBb_t-IlWCjyTdbMDWQZpnSyAqvNBPfag3d2xLIToFlpfRVOzt7H6RDT6UFPMQp4mU2y1LB-mjyxJE1USqGO3XabozW4b13cnbWtYpqCpdyGa1s8tCVKIOZCi5Bumcgz1MaKId_VnjGRnc3nC7nHCaaN9oJS8ijylfR0LJx1mEZGehMYYebEsQylNrZrlJJaidDzjQmFdl1lV-B4ItBAFVDjNPGiH-QgyTwgSQQkiQoclKTDHF_jJ6LqRCtB4WKjgKo21FgrnQrsl4_ROeiPR5jo9IVoCMHOl76owEauzZILx9xSCL-Oi82U9jv74AHFShdbfyfdg7n23XUn6Fx2r7ZhHhfi58ckqzA9fn7ROzCrXse90fNuYbQfso3s6g
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1ZS8NAEB5KFfHFqx71XEXEB4PNJtlkwZdiDYqllGLRt5BsdkVok9JD8d-7k6QRUUHwLSQTZpkjMzvZ-Qbg1LJiK6SUG6ZwhN6gOMyIYss0Yq9hOVLnEyxH12-7nY739MS7Fbia98Lk-BBlwQ09I_teo4PLUawuP1FD37SotaNjA_mCjUNkqrDQ6vn9dllj0QZK3WwErw6SroFI7nNwoQa9LN__GpK-5Zlf09Ys7vir_1vxGqwU-SZp5gayDhWZbECtmei99vCdnJHsBGhWWq_BxfX7NB3pdHr4IggGvMwmSarIIE2eSZImIsVQR3qd5mQT-v7Nw_WtUUxTMITt2KZBQ5NrCcSUSRbiLRW5CttYdci3patUZGbz-ULqUoRpw70g5zSKPMFdGTNrC6qakdwBgpg5ccxDLpVpKyG4FCx0PaVCJm1bmHU4nws0EAXUOE68GAQ5SDINUBIBSqIOJyXpKMfX-Ilof66VoHCxSYBVG2ys5VYdjsvH2jnwj0eYyHSGNIhg53GP1WE712bJherckjGvoRebKe139sGjFite7P6d9AiWui0_aN917vdgWa_Dy09J7kN1Op7JA1gUr9OXyfiwsNkPWWTsZQ
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cytoplasmic+functions+of+long+noncoding+RNAs&rft.jtitle=Wiley+interdisciplinary+reviews.+RNA&rft.au=Noh%2C+Ji+Heon&rft.au=Kim%2C+Kyoung+Mi&rft.au=McClusky%2C+Waverly+G.&rft.au=Abdelmohsen%2C+Kotb&rft.date=2018-05-01&rft.pub=John+Wiley+%26+Sons%2C+Inc&rft.issn=1757-7004&rft.eissn=1757-7012&rft.volume=9&rft.issue=3&rft.epage=n%2Fa&rft_id=info:doi/10.1002%2Fwrna.1471&rft.externalDBID=10.1002%252Fwrna.1471&rft.externalDocID=WRNA1471
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1757-7004&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1757-7004&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1757-7004&client=summon