Development of Host Immune Response to Bacteriophage in a Lung Transplant Recipient on Adjunctive Phage Therapy for a Multidrug-Resistant Pneumonia

Bacteriophage therapy is the use of viruses to kill bacteria for the treatment of antibiotic-resistant infections. Little is known about the human immune response following phage therapy. We report the development of phage-specific CD4 T cells alongside rising phage-specific immunoglobulin G and neu...

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Veröffentlicht in:	The Journal of infectious diseases Jg. 227; H. 3; S. 311
Hauptverfasser:	Dan, Jennifer M, Lehman, Susan M, Al-Kolla, Rita, Penziner, Samuel, Afshar, Kamyar, Yung, Gordon, Golts, Eugene, Law, Nancy, Logan, Cathy, Kovach, Zsuzsanna, Mearns, Gill, Schooley, Robert T, Aslam, Saima, Crotty, Shane
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.02.2023
Schlagworte:	Bacteriophages - physiology Humans Immunity Lung - microbiology Phage Therapy Pneumonia Pseudomonas aeruginosa - physiology Pseudomonas Infections - microbiology Pseudomonas Infections - therapy Transplant Recipients AIM immune response phage therapy anti-phage antibody PBMC bacteriophage T follicular helper cell
ISSN:	1537-6613, 1537-6613
Online-Zugang:	Weitere Angaben
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