Lassa fever: implications of T-cell immunity for vaccine development

Lassa fever is a re-emerging viral hemorrhagic fever, which causes significant human morbidity in endemic regions of West Africa. Attempts to vaccinate against this virus in animal models including non-human primates have revealed that eliciting a strong cellular immune response protects from clinic...

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Bibliographic Details
Published in:	Journal of biotechnology Vol. 73; no. 2; pp. 207 - 212
Main Author:	ter Meulen, J
Format:	Journal Article Conference Proceeding
Language:	English
Published:	Lausanne Elsevier B.V 20.08.1999 Amsterdam Elsevier New York, NY
Subjects:	Animals Antibodies Assays Biological and medical sciences Biotechnology Cells Diseases Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Humans Immunization Industrial applications and implications. Economical aspects Lassa Fever - immunology Lassa Fever - prevention & control Lassa virus Lassa virus - immunology Lymphocyte Activation Lymphocytic choriomeningitis virus - immunology Physiological models Production of active biomolecules Proteins T-cell immunity T-Lymphocytes - immunology Vaccine development Vaccins Viral Vaccines - isolation & purification Viruses T-cell immunity Vaccine development Lassa virus Infection Virus Human Lassa fever Viral disease Pathogenic Cellular immunity Vaccine Review Arenaviridae Arenavirus
ISSN:	0168-1656, 1873-4863
Online Access:	Get full text
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