Cardiovascular Outcomes with Sotagliflozin

To the Editor: In the SOLOIST-WHF trial (Effect of Sotagliflozin on Cardiovascular Events in Patients with Type 2 Diabetes Post Worsening Heart Failure), Bhatt et al. (Jan. 14 issue) 1 report that death from cardiovascular causes and hospitalizations and urgent visits for heart failure (the composit...

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Published in:The New England journal of medicine Vol. 384; no. 15; pp. 1470 - 1473
Main Authors: Baglioni, Piero, Marchand, Lucien, Villar, Emmanuel, Green, Lisa, Bhatt, Deepak L, Steg, P. Gabriel, Pitt, Bertram
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 15.04.2021
Subjects:
Cardiovascular diseases
Congestive heart failure
Diabetes
Diabetes mellitus (non-insulin dependent)
Diabetic Ketoacidosis
Glycosides
Heart failure
Humans
Mortality
Placebos
Renal Insufficiency, Chronic
ISSN:0028-4793, 1533-4406, 1533-4406
Online Access:Get full text
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Summary:To the Editor: In the SOLOIST-WHF trial (Effect of Sotagliflozin on Cardiovascular Events in Patients with Type 2 Diabetes Post Worsening Heart Failure), Bhatt et al. (Jan. 14 issue) 1 report that death from cardiovascular causes and hospitalizations and urgent visits for heart failure (the composite primary outcome) occurred in fewer patients in the sotagliflozin group than in the placebo group. This benefit was also seen in the SCORED trial (Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk) reported by Bhatt et al. (also in Jan. . . .
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMc2102961