The silent war of CMV in aging and HIV infection

•Importance of to human health.•Replicative senescence within the human immune system.•Senescent T cells accumulate with age.•Cytomegalovirus is a major driver of senescence.•Cytomegalovirus impacts both normal aging and HIV/AIDS. Human cytomegalovirus (CMV), the prototypical β-herpervirus, is a wid...

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Vydané v:	Mechanisms of ageing and development Ročník 158; s. 46 - 52
Hlavný autor:	Effros, Rita B.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Ireland Elsevier Ireland Ltd 01.09.2016
Predmet:	Acquired Immunodeficiency Syndrome - immunology Acquired Immunodeficiency Syndrome - pathology Aging Aging - immunology Aging - pathology Animals CD8T cell CMV Cytomegalovirus - immunology Cytomegalovirus Infections - immunology Cytomegalovirus Infections - pathology HIV HIV-1 - immunology Humans Immunity, Cellular Replicative senescence Aging CD8T cell Replicative senescence HIV CMV
ISSN:	0047-6374, 1872-6216
On-line prístup:	Získať plný text
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