Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats

Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain and an extensive array of other symptoms including disordered sleep, fatigue, depression and anxiety. Important factors involved in the pathogenic process of fibromyalgia are inflammation and oxidative stress, sugges...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 18; no. 7; p. 1389
Main Authors:	Favero, Gaia, Trapletti, Valentina, Bonomini, Francesca, Stacchiotti, Alessandra, Lavazza, Antonio, Rodella, Luigi, Rezzani, Rita
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI 29.06.2017
Subjects:	Administration, Oral Analysis of Variance Animals Antioxidants - pharmacology Body Weight - drug effects Disease Models, Animal Fibromyalgia - drug therapy Inflammation - drug therapy Male Melatonin - pharmacology Microscopy, Electron, Transmission Muscle, Skeletal - drug effects Muscle, Skeletal - pathology Muscle, Skeletal - ultrastructure Musculoskeletal Diseases - drug therapy Myalgia - drug therapy Oxidative Stress - drug effects Protective Agents - pharmacology Rats Rats, Sprague-Dawley Reserpine - pharmacology Sulfhydryl Compounds - analysis melatonin skeletal muscle fibromyalgia inflammation oxidative stress
ISSN:	1422-0067, 1422-0067
Online Access:	Get full text
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