Angiosarcoma: clinical and imaging features from head to toe

Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; howeve...

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Vydané v:British journal of radiology Ročník 90; číslo 1075; s. 20170039
Hlavní autori: Gaballah, Ayman H, Jensen, Corey T, Palmquist, Sarah, Pickhardt, Perry J, Duran, Alper, Broering, Gregory, Elsayes, Khaled M
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England The British Institute of Radiology 01.07.2017
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ISSN:0007-1285, 1748-880X, 1748-880X
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Abstract Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; however, there is a predilection for the skin where half of all tumours arise, increasing in prevalence with age. The most common risk factors are chronic lymphoedema and history of radiation. We review the most important radiological findings along the spectrum of angiosarcoma from head to toe throughout the body, including uncommon and rare locations. Key imaging features of angiosarcoma across multiple organ systems will be described, as well as the impact on management and prognosis.
AbstractList Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; however, there is a predilection for the skin where half of all tumours arise, increasing in prevalence with age. The most common risk factors are chronic lymphoedema and history of radiation. We review the most important radiological findings along the spectrum of angiosarcoma from head to toe throughout the body, including uncommon and rare locations. Key imaging features of angiosarcoma across multiple organ systems will be described, as well as the impact on management and prognosis.
Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; however, there is a predilection for the skin where half of all tumours arise, increasing in prevalence with age. The most common risk factors are chronic lymphoedema and history of radiation. We review the most important radiological findings along the spectrum of angiosarcoma from head to toe throughout the body, including uncommon and rare locations. Key imaging features of angiosarcoma across multiple organ systems will be described, as well as the impact on management and prognosis.Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; however, there is a predilection for the skin where half of all tumours arise, increasing in prevalence with age. The most common risk factors are chronic lymphoedema and history of radiation. We review the most important radiological findings along the spectrum of angiosarcoma from head to toe throughout the body, including uncommon and rare locations. Key imaging features of angiosarcoma across multiple organ systems will be described, as well as the impact on management and prognosis.
Author Gaballah, Ayman H
Palmquist, Sarah
Elsayes, Khaled M
Broering, Gregory
Jensen, Corey T
Pickhardt, Perry J
Duran, Alper
Author_xml – sequence: 1
  givenname: Ayman H
  surname: Gaballah
  fullname: Gaballah, Ayman H
– sequence: 2
  givenname: Corey T
  surname: Jensen
  fullname: Jensen, Corey T
– sequence: 3
  givenname: Sarah
  surname: Palmquist
  fullname: Palmquist, Sarah
– sequence: 4
  givenname: Perry J
  surname: Pickhardt
  fullname: Pickhardt, Perry J
– sequence: 5
  givenname: Alper
  surname: Duran
  fullname: Duran, Alper
– sequence: 6
  givenname: Gregory
  surname: Broering
  fullname: Broering, Gregory
– sequence: 7
  givenname: Khaled M
  surname: Elsayes
  fullname: Elsayes, Khaled M
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28471264$$D View this record in MEDLINE/PubMed
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Snippet Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor...
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StartPage 20170039
SubjectTerms Diagnosis, Differential
Hemangiosarcoma - diagnostic imaging
Hemangiosarcoma - etiology
Hemangiosarcoma - pathology
Humans
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Other
Predictive Value of Tests
Prognosis
Review
Risk Factors
Title Angiosarcoma: clinical and imaging features from head to toe
URI https://www.ncbi.nlm.nih.gov/pubmed/28471264
https://www.proquest.com/docview/1895278574
https://pubmed.ncbi.nlm.nih.gov/PMC5594986
Volume 90
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