Angiosarcoma: clinical and imaging features from head to toe

Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; howeve...

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Bibliographic Details
Published in:British journal of radiology Vol. 90; no. 1075; p. 20170039
Main Authors: Gaballah, Ayman H, Jensen, Corey T, Palmquist, Sarah, Pickhardt, Perry J, Duran, Alper, Broering, Gregory, Elsayes, Khaled M
Format: Journal Article
Language:English
Published: England The British Institute of Radiology 01.07.2017
Subjects:
Diagnosis, Differential
Hemangiosarcoma - diagnostic imaging
Hemangiosarcoma - etiology
Hemangiosarcoma - pathology
Humans
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Other
Predictive Value of Tests
Prognosis
Review
Risk Factors
ISSN:0007-1285, 1748-880X, 1748-880X
Online Access:Get full text
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Summary:Angiosarcoma is a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; however, there is a predilection for the skin where half of all tumours arise, increasing in prevalence with age. The most common risk factors are chronic lymphoedema and history of radiation. We review the most important radiological findings along the spectrum of angiosarcoma from head to toe throughout the body, including uncommon and rare locations. Key imaging features of angiosarcoma across multiple organ systems will be described, as well as the impact on management and prognosis.
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ISSN:0007-1285
1748-880X
1748-880X
DOI:10.1259/bjr.20170039