Next‐generation sequencing improves molecular epidemiological characterization of thalassemia in Chenzhou Region, P.R. China

Objectives Thalassemia is a highly prevalent monogenic inherited disease in southern China. It is important to collect epidemiological data comprehensively for proper prevention and treatment. Methods In this study, blood samples collected from 15 807 residents of Chenzhou were primarily screened by...

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Vydáno v:	Journal of clinical laboratory analysis Ročník 33; číslo 4; s. e22845 - n/a
Hlavní autoři:	Zhang, Haoqing, Li, Caiyun, Li, Jianbiao, Hou, Shuai, Chen, Danjing, Yan, Haiying, Chen, Shiping, Liu, Saijun, Yin, Zhenzhen, Yang, Xiaoqin, Tan, Jufang, Huang, Xiaoyan, Zhang, Liming, Fang, Junbin, Zhang, Caifen, Li, Wei, Guo, Jian, Lei, Dongzhu
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States John Wiley & Sons, Inc 01.05.2019 John Wiley and Sons Inc
Témata:	Adolescent Adult alpha-Thalassemia - epidemiology alpha-Thalassemia - genetics beta-Thalassemia - epidemiology beta-Thalassemia - genetics Child Child, Preschool China - epidemiology Epidemiology Female Genetic analysis Genetic Carrier Screening Hemoglobin Hemoglobins, Abnormal - genetics Hereditary diseases High-Throughput Nucleotide Sequencing Humans Infant Male Middle Aged Molecular Epidemiology Mutation next‐generation sequencing Polymerase Chain Reaction - methods prevalence Thalassemia variant Young Adult China variant mutation prevalence thalassemia next-generation sequencing
ISSN:	0887-8013, 1098-2825, 1098-2825
On-line přístup:	Získat plný text
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